Explore: Complement Activation

amplifies the complement activation. When complement is activated on a cell surface, the activation is limited by endogenous complement regulatory proteins

distinct from the other complement pathways in its unique activation triggers and cascade sequence. Activation of the complement pathway through the classical

antibodies, which include pathogen and toxin neutralization, classical complement activation, and opsonin promotion of phagocytosis and pathogen elimination

central role in the activation of the complement system. Its activation is required for both classical and alternative complement activation pathways. People

prevent complement activation from proceeding on the host cell, there are several different kinds of regulatory proteins that disrupt the complement activation

lectin pathways of complement activation, formation of the C3-convertase and C5-convertases requires binding of C2 to an activated surface-bound C4b in

terminal complement complex (TCC) is a complex of proteins typically formed on the surface of pathogen cell membranes as a result of the activation of the

"regulators of complement activation (RCA)" that help distinguish target cells as "self" or "non-self." A subset of this family of proteins, complement control

Cell-Bound Complement Activation Products (CB-CAPs) or complement split products, refers to complement activation fragments, C4d, that are bound covalently

encoded by the CR1 gene. This gene is a member of the regulators of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome