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Source: The Open Library

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1V(D)J recombination

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“V(D)J recombination” Metadata:

  • Title: V(D)J recombination
  • Author:
  • Language: English
  • Publisher: ➤  Springer Science+Business Media - Landes Bioscience - Springer London, Limited
  • Publish Date:
  • Publish Location: New York, N.Y - Austin, Tex

“V(D)J recombination” Subjects and Themes:

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Access and General Info:

  • First Year Published: 2009
  • Is Full Text Available: No
  • Is The Book Public: No
  • Access Status: No_ebook

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V(D)J recombination

majority of T cells. The process of V(D)J recombination is mediated by VDJ recombinase, which is a diverse collection of enzymes. The key enzymes involved

Recombination signal sequences

intervening DNA and creating a double-stranded break that is repaired by VDJ recombinase enzymes. This process is repeated for the joining of V to DJ. In light-chain

Recombination-activating gene

genes (the VDJ genes) to create millions of permutations, in a process called V(D)J recombination. RAG-1 and RAG-2 are proteins at the ends of VDJ genes that

Cortical thymic epithelial cells

Essential part of T cell development forms process called VDJ recombination, mediated by RAG recombinases, that stochastically changes DNA sequences of T cell

T-cell receptor

is generated by VJ recombination, whereas the beta chain is generated by VDJ recombination (both involving a random joining of gene segments to generate

List of MeSH codes (D08)

rec a recombinases MeSH D08.811.739.650.500 – rad51 recombinase MeSH D08.811.739.800 – transposon resolvases MeSH D08.811.739.900 – vdj recombinases MeSH D08