Explore: Substrate Specificity

ligands. The fewer ligands a protein can bind, the greater its specificity. Specificity describes the strength of binding between a given protein and ligand

computationally switch the specificities of A-domains. The condensation C-domain is also believed to have substrate specificity, especially if located behind

active site. These enzymes can be further categorised based on their substrate specificity as either trypsin-like, chymotrypsin-like or elastase-like. Trypsin-like

different substrates (i.e., substrate specificity). The higher the specificity constant, the more the enzyme "prefers" that substrate. The following equation

identify the substrate specificity of protein kinases toward synthetic peptides. This approach was then extended to characterize the specificity of Ser/Thr

sequences on their substrates and hydrolyze peptide bonds after aspartic acid residues. Caspase 3 and caspase 7 share similar substrate specificity by recognizing

Raven EL (August 2003). "Understanding functional diversity and substrate specificity in haem peroxidases: what can we learn from ascorbate peroxidase

strictly tyrosine-specific, and the DSPs (c) which target Ser/Thr as well as Tyr and are the most diverse in terms of substrate specificity. The third class

substrate specificity is largely determined by specific side chains which line the aqueous pocket at the center of the membrane. While one substrate of

complexity. Evolutionary modification in substrate specificity is seen most drastically in the amino acid substrate. OcDH from some sea anemones has been