Explore: Rectal Absorption

Rectal administration (colloquially known as boofing or plugging) uses the rectum as a route of administration for medication and other fluids, which are

on clinical signs, presence of reflux, rectal exam, and ultrasound. Often the impaction can not be felt on rectal due to distended small intestinal loops

Rectal discharge is intermittent or continuous expression of liquid from the anus (per rectum). Normal rectal mucus is needed for proper excretion of

than that of the oral route. Rectal mucosa is highly vascularized tissue that allows for rapid and effective absorption of medications. A suppository

to the stomach (PEG tube). Rectal administration usually involves rectal suppositories.) The mechanism for drug absorption from the intestine is for most

chlorobutanol and caffeine (for the treatment of hyperemesis). However, rectal absorption is less efficient than oral: the maximum concentration (Cmax) and

to be caused by high levels of plasma aldosterone, which leads to rectal absorption of sodium and water. Also expected is the production of hyperosmotic

Fortunio G (1952). "[Absorption and action of testosterone administered rectally]" [Absorption and action of testosterone administered rectally]. Clinica Nuova;

The absorption of the rectal route is variable, with a wide range of maximal concentrations of 15 to 52 ng/mL progesterone after a single rectal dose

rectal route of administration is highly effective as the rectal mucosa is highly vascularized tissue that allows for rapid and effective absorption of