Explore: Recombinant Poxviruses

boosted by the administration of recombinant protein or recombinant poxviruses. "Prime-boost" strategies with recombinant protein have successfully increased

infection) or through the JAK-STAT pathway (as with DEN-2 infection). Several poxviruses encode soluble IFN receptor homologs—like the B18R protein of the vaccinia

flaviviruses, measles viruses, rhabdoviruses, Newcastle disease virus, poxviruses, and picornaviruses. Most vaccines consist of viruses that have been attenuated

Lecocq JP, Mackett M (1984). "Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene". Proc. Natl. Acad. Sci

Michael E. G.; Boyle, David B.; Brochier, Bernard; et al. (1992). Recombinant Poxviruses. Boca Raton, Florida, United States: CRC Press. pp. 1–343. ISBN 0-8493-6179-6

tumor-associated antigen prostate-specific antigen (PSA). PROSTVAC utilizes recombinant poxviruses that express PSA, along with 3 immune-enhancing costimulatory molecules

September 2011. Binns, Matthew M.; Smith, Geoffrey L. (27 May 1992). Recombinant Poxviruses. CRC Press. ISBN 978-0849361791. Smith, G. L.; Irving, W. L.; McCauley

viruses which cause the afflicted organism to have poxes as a symptom. Poxviruses have generally large genomes, and other such examples include smallpox

used in recombinant vaccines, as a vector for expression of foreign genes within a host, in order to generate an immune response. Other poxviruses are also

The life cycle of poxviruses is complicated by having multiple infectious forms, with differing mechanisms of cell entry. Poxviruses are unique among human