Explore: Proteolysis

years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Proteolysis in organisms

A proteolysis targeting chimera (PROTAC) is a molecule that can remove specific unwanted proteins. Rather than acting as a conventional enzyme inhibitor

(limited proteolysis), depending on the amino acid sequence of a protein, or completely break down a peptide to amino acids (unlimited proteolysis). The

The Proteolysis MAP (PMAP) was an integrated web resource focused on proteases. Its domain now links to a scam/spam browser extender. PMAP was designed

biotechnological processes. The process is commonly referred to as trypsinogen proteolysis or trypsinization, and proteins that have been digested/treated with

A heat-stable polypeptide present in these extracts, ATP-dependent proteolysis factor 1 (APF-1), was found to become covalently attached to the model

essential protein complexes responsible for the degradation of proteins by proteolysis, a chemical reaction that breaks peptide bonds. Enzymes that help such

ubiquitin, which directs the complex to the proteasome Degradation by proteolysis of both the protein capsid and the antibody occurs, but not the TRIM21

Vepdegestrant is an experimental estrogen receptor degrader that works via proteolysis targeting chimera. It is developed for advanced estrogen receptor positive

Bavdegalutamide is an experimental proteolysis targeting chimera that functions as a androgen receptor degrader. It is being developed to treat metastatic