Explore: Protein Interaction Domains And Motifs

and John M. Jumper for computational protein design and protein structure prediction). Zinc finger (Znf) domains are relatively small protein motifs that

identification of recurring motifs, for example the Greek key motif. α+β domains are a mixture of all-α and all-β motifs. Classification of proteins into this class

domains known as MH1 and MH2. The complex of two SMAD3 (or of two SMAD2) and one SMAD4 binds directly to DNA though interactions of their MH1 domains

DNA-binding proteins are proteins that have DNA-binding domains and thus have a specific or general affinity for single- or double-stranded DNA. Sequence-specific

Protein–protein interaction prediction is a field combining bioinformatics and structural biology in an attempt to identify and catalog physical interactions

prototypical modular protein-protein interaction domain, allowing the transmission of signals controlling a variety of cellular functions. SH2 domains are especially

different proteins expressed in eukaryotic systems, there are many fewer different domains, structural motifs and folds. A structural domain is an element

(September 1996). "Structural classification of HTH DNA-binding domains and protein-DNA interaction modes". Journal of Molecular Biology. 262 (2): 294–313. doi:10

of the protein and contains four motifs: two verprolin homology motifs (VV) binds actin monomers and delivers them to Arp2/3; the central domain (C) was

sequences within proteins often act as recognition sites for other proteins. For instance, SH3 domains typically bind to short PxxP motifs (i.e. 2 prolines