Explore: Prostanoids

In molecular biology, prostanoids are active lipid mediators that regulate inflammatory response. Prostanoids are a subclass of eicosanoids consisting

HEPEs, leukotrienes, prostanoids, and epoxyeicosatetraenoic acids as well as the metabolism of dihomo-gamma-linolenic acid to prostanoids and mead acid to

series 2 prostanoids, i.e. PGD2, PGE2, PGF2α, PGI2, TXA2 and PGH2. However, the same enzymes that metabolize arachidonic acid to series 2 prostanoids similarly

family of isozymes, EC 1.14.99.1) that is responsible for biosynthesis of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from

but generally with lesser affinity and responsiveness to certain other prostanoids (see Prostaglandin receptors). Animal model studies have implicated EP1

but generally with lesser affinity and responsiveness, certain other prostanoids (see Prostaglandin receptors). EP has been implicated in various physiological

immune, pulmonary and neurological tissues, among others. Standard prostanoids have the following relative efficacies as receptor ligands in binding

proliferation of various human cancer cell lines in culture. Prostanoids and Prostaglandin receptors Prostanoids are prostaglandins (PG), thromboxanes (TX), and prostacyclins

lead to uterine rupture, which requires immediate emergency surgery. Prostanoids, including alprostadil, do not reduce the risk of limb amputation but

A, Narumiya S (August 2000). "Roles of prostanoids revealed from studies using mice lacking specific prostanoid receptors". Japanese Journal of Pharmacology