Explore: Oligonucleotides

for the use of oligonucleotides as probes for detecting specific sequences of DNA or RNA. Examples of procedures that use oligonucleotides include DNA microarrays

custom-made oligonucleotides of the desired sequence. Whereas enzymes synthesize DNA and RNA only in a 5' to 3' direction, chemical oligonucleotide synthesis

Fluorescent modifications on 5' and 3' end of oligonucleotides was reported to evaluate the oligonucleotides structures, dynamics and interactions with respect

common stem for antisense oligonucleotides drugs is -rsen. The substem -virsen designates antiviral antisense oligonucleotides. Developments in ASO modification

electrochemistry on microelectrode arrays. In spotted microarrays, the probes are oligonucleotides, cDNA or small fragments of PCR products that correspond to mRNAs.

amplified sample DNA is used for hybridization. The use of synthetic oligonucleotides as specific probes for genetic sequence variations was pioneered by

oligonucleotides. Combination of exceptional targeting capabilities of monoclonal antibodies with numerous functional modalities of oligonucleotides has

DNAzymes. Using LNA based oligonucleotides therapeutically is an emerging field in biotechnology. A variety of LNA oligonucleotides have been assessed for

A nucleic acid sequence is a succession of bases within the nucleotides forming alleles within a DNA (using GACT) or RNA (GACU) molecule. This succession

complementary nucleic acids or primers for polymerase chain reaction. Oligonucleotides labeled with fluorescein at one of the termini and with a quencher