Explore: Nucleophiles

can act as nucleophiles. Because nucleophiles donate electrons, they are Lewis bases. Nucleophilic describes the affinity of a nucleophile to bond with

G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved in

broadened to include nucleophiles other than enolates. Some examples of nucleophiles include doubly stabilized carbon nucleophiles such as beta-ketoesters

Nucleophilic substitution reactions are common in organic chemistry. Nucleophiles often attack a saturated aliphatic carbon. Less often, they may attack

reactions. Embedding the nucleophile in a triad increases its reactivity for efficient catalysis. The most commonly used nucleophiles are the hydroxyl (OH)

polar protic solvents include water and alcohols, which will also act as nucleophiles, and the process is known as solvolysis. The Y scale correlates solvolysis

than as a nucleophile, abstracting a proton and leading to formation of the alkene. This pathway is favored with sterically hindered nucleophiles. Elimination

chemistry, an electrophile is a chemical species that forms bonds with nucleophiles by accepting an electron pair. Because electrophiles accept electrons

atoms is the hydroxy group. Both the hydroxide ion and hydroxy group are nucleophiles and can act as catalysts in organic chemistry. Many inorganic substances

nonclassical ions as intermediates or transition states. For certain nucleophiles, solvolysis reactions are classified. Solvolysis involving water is called