Explore: Methylation

Methylation, in the chemical sciences, is the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group.

DNA methylation is a biological process by which methyl groups are added to the DNA molecule. Methylation can change the activity of a DNA segment without

nucleotide sequence. Examples of mechanisms that produce such changes are DNA methylation and histone modification, each of which alters how genes are expressed

Mercury methylation is the process of forming methylmercury (MeHg). The methylation of mercury can occur abiotically or biotically. Biotically, the primary

Histone methylation is a process by which methyl groups are transferred to amino acids of histone proteins that make up nucleosomes, which the DNA double

suppressed via methylation, further TE's can act as "methylation centres" facilitating methylation of flanking DNA. Since methylation reduces selective

most common modifications are the methylation of arginine or lysine residues or the acetylation of lysine. Methylation can affect how other proteins such

of DNA before routine sequencing to determine the pattern of methylation. DNA methylation was the first discovered epigenetic mark, and remains the most

The Illumina Methylation Assay using the Infinium I platform uses 'BeadChip' technology[clarification needed] to generate a comprehensive genome-wide

2'-O-methylation (2'-O-Me) is a nucleotide epitranscriptomics modification commonly found in ribosomal RNA (rRNA), transfer RNA (tRNA), and small nuclear