Explore: Hemoglobinopathies

Hemoglobinopathy is the medical term for a group of inherited blood disorders involving the hemoglobin, the major protein of red blood cells. They are

heterozygosity. Both alpha- and beta- thalassemia can coexist with other hemoglobinopathies. Combinations involving alpha thalassemia are generally benign. Some

combination hemoglobinopathy occurs when someone inherits two different abnormal hemoglobin genes. Alpha thalassemia can coexist with other hemoglobinopathies such

increase as a consequence of stress erythropoiesis. Checking for hemoglobinopathies begins during pregnancy, with a prenatal screening questionnaire which

hematological malignancies such as lymphoma and leukemia (cancers) treating hemoglobinopathies, including α-thalassemias and β-thalassemias (thalassemia syndromes)

the bone marrow to produce red blood cells), and certain hereditary hemoglobinopathies (including some cases of thalassemia minor) may all present with a

cell disease and complications from chemotherapy or transfusions. Hemoglobinopathies (congenital abnormality of the hemoglobin molecule or of the rate

resistance. Hemoglobinopathies are a class of monogenic disorders that impact the major red blood cell protein hemoglobin. Hemoglobinopathies interfere

some cause a group of hereditary diseases called hemoglobinopathies. The best known hemoglobinopathy is sickle-cell disease, which was the first human

under the broad category of hemoglobinopathies. Worldwide, it is estimated that 7% of the population may carry a hemoglobinopathy with clinical significance