Explore: Difenoxin

Difenoxin (Motofen, R-15403) is an opioid drug used, often in combination with atropine, to treat diarrhea. It is the principal metabolite of diphenoxylate

is effective and safe for treating chronic diarrhea. Diphenoxylate and difenoxin work similarly but can affect the brain at high doses, so they're combined

(sold in the U.S. as Nuvigil) Difenoxin, an antidiarrheal drug, when combined with atropine (such as Motofen) (difenoxin is 2–3 times more potent than

Bensinger, Peter (August 28, 1978). "Placement of Preparations Containing Difenoxin in Combination With Atropine Sulfate Into Schedules IV and V" (PDF). Isomer

name for an antiperistaltic anti-diarrheal medication, containing 1.0 mg difenoxin HCl and 0.025 mg atropine (U.S. Food and Drug Administration: Schedule

of appetite, and stomach pain. Diphenoxylate is rapidly metabolized to difenoxin; it is eliminated mostly in feces but also in urine. Like other opioids

Jerry (May 7, 1975). "Schedules of Controlled Substances: Placement of Difenoxin in Schedule I" (PDF). Isomer Design. Drug Enforcement Administration.

drugs, particularly antidiarrhea opioid drugs such as diphenoxylate or difenoxin, wherein the secretion-reducing effects of the atropine can also aid the

Bezitramide Piritramide Methadone Dipipanone Levomethadyl acetate (LAAM) Difenoxin Diphenoxylate Loperamide (does cross the blood–brain barrier but is quickly

4-phenylpiperidine opioids – pethidines (meperidines): anileridine benzethidine difenoxin diphenoxylate etoxeridine furethidine hydroxypethidine morpheridine pethidine