Explore: Clozapine

Clozapine, sold under the brand name Clozaril among others, is a psychiatric medication and was the first atypical antipsychotic to be discovered. It

Clozapine N-oxide (CNO) is a synthetic drug used mainly in biomedical research as a ligand to activate Designer Receptors Exclusively Activated by Designer

in combination with an SSRI antidepressant. But it is less potent than clozapine, amisulpride, olanzapine, risperidone, and paliperidone in alleviating

antipsychotics, known as atypical antipsychotics, arrived with the introduction of clozapine in the early 1970s followed by others (e.g., risperidone, olanzapine,

antipsychotics, in which case clozapine is offered. In a network comparative meta-analysis of 15 antipsychotic drugs, clozapine was significantly more effective

member of the dibenzoxazepine class and structurally very similar to clozapine. Several researchers have argued that loxapine, initially classified as

quit before the 6-week completion date. Treatment with olanzapine (like clozapine) may result in increased weight gain and increased glucose and cholesterol

a major active metabolite of the atypical antipsychotic drug clozapine. Unlike clozapine, it possesses intrinsic activity at the D2/D3 receptors, and

DHA-clozapine (tentative trade name Clozaprexin) is an atypical antipsychotic drug candidate that was created and originally tested by chemists at Protarga

cases of bowel obstruction or constipation (such as those related to clozapine treatment) fecal vomiting has been identified as a cause of death. Fecal