Explore: Bone Metastasis

Bone metastasis, or osseous metastatic disease, is a category of cancer metastases that result from primary tumor invasions into bones. Bone-originating

breath) Liver metastasis: hepatomegaly (enlarged liver), nausea and jaundice Bone metastasis: bone pain, fracture of affected bones Brain metastasis: neurological

apoptosis of tumour cells. Bone is a common site of metastasis in cancers such as breast, prostate and lung cancer. In osteolytic bone metastases, tumour cells

the prevention and treatment of osteoporosis, Paget's disease of bone, bone metastasis (with or without hypercalcemia), multiple myeloma, primary hyperparathyroidism

In breast cancer, spinal-cord compression occurs when a bone metastasis or spinal metastasis begins to push on the spinal cord, resulting in inflammation

cases of bone cancer is systemic radioisotope therapy, where the radioisotopes target sections of the bone specifically undergoing metastasis. In the case

cancer of the bone or metastasis, location of bone inflammation and fractures (that may not be visible in traditional X-ray images), and bone infection (osteomyelitis)

Antonarakis, Emmanuel S. (October 2012). "Bone-targeting radiopharmaceuticals for the treatment of prostate cancer with bone metastases". Cancer Letters. 323 (2):

Metastasis is common in the late stages of cancer and it can occur via the blood or the lymphatic system or both. The typical steps in metastasis are:

cancer causes hypercalcemia is via local osteolysis due to metastasis to bone. Tumor bone metastasis releases local cytokines including IL-6, IL-8, IL-11,