Explore: Alkylating Agents

Classification System, alkylating agents are classified under L01A. Many of the agents are known as "classical alkylating agents". These include true alkyl

oxide is the alkylating group in this reaction. In the process called oxidative addition, low-valent metals often react with alkylating agents to give metal

treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) in a standard regimen. Chemotherapy may be given with a curative

effectiveness, purine analogs are most frequently administered. The alkylating agents used in immunotherapy are nitrogen mustards (cyclophosphamide), nitrosoureas

electrophilic aromatic substitution. In commercial applications, the alkylating agents are generally alkenes, some of the largest scale reactions practiced

carbonyl species (RCS), lipid peroxidation products, adducts, and alkylating agents through metabolic processes. ROS is one of the major endogenous sources

are potent alkylating agents, making mustard gas acutely and severely toxic. Mustard gas is a carcinogen. There is no preventative agent against mustard

used to destroy cancer cells. Alkylating agents such as cyclophosphamide and cisplatin, as well as intercalating agent such as daunorubicin and doxorubicin

structure or affect its replication or transcription functions (e.g., alkylating agents, antitumor antibiotics, and platinum complexes). These drugs often

Some people have a history of exposure to chemotherapy (especially alkylating agents such as melphalan, cyclophosphamide, busulfan, and chlorambucil) or