Explore: Acetanilide

Acetanilide is the organic compound with the formula C6H5NHC(O)CH3. It is the N-acetylated derivative of aniline. It is an odourless solid chemical of

L. A. (1947), "Metabolic fate of acetanilide and other aniline derivatives. II. Major metabolites of acetanilide in the blood", J. Pharmacol. Exp. Ther

of acetanilide and phenacetin. In 1947, David Lester and Leon Greenberg found strong evidence that paracetamol was a major metabolite of acetanilide in

stomach, or acid indigestion. It originally contained sodium bromide and acetanilide, both toxic substances which were eventually removed. Its current formulation

organic compounds as possible new medicines, following the success of acetanilide ten years earlier. Two years later, Bayer created acetylsalicylic acid

aniline are sometimes called anilides, for example CH3−C(=O)−NH−C6H5 is acetanilide. At high temperatures aniline and carboxylic acids react to give the

Yale, he coauthored with Leon Greenberg a series of three papers on acetanilide, an analgesic that was still in use at the time, aiming to establish

is a substance that increases the rate of a chemical reaction. Added acetanilide slows the decomposition of drug-store hydrogen peroxide solution, inhibiting

Tilidine Tramadol (+celecoxib, +paracetamol) Viminol Paracetamol-type Acetanilide‡ Bucetin‡ Butacetin‡ Paracetamol (acetaminophen)# +aspirin/caffeine +butalbital

Mehta S (25 August 2012). "Metabolism of Paracetamol (Acetaminophen), Acetanilide and Phenacetin". PharmaXChange.info. Archived from the original on 28