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methods and protocols

"Therapeutic applications of ribozymes and riboswitches" was published by Humana Press in 2014 - New York, it has 278 pages and the language of the book is English.


“Therapeutic applications of ribozymes and riboswitches” Metadata:

  • Title: ➤  Therapeutic applications of ribozymes and riboswitches
  • Authors:
  • Language: English
  • Number of Pages: 278
  • Publisher: Humana Press
  • Publish Date:
  • Publish Location: New York

“Therapeutic applications of ribozymes and riboswitches” Subjects and Themes:

Edition Specifications:

  • Pagination: xi, 278 pages

Edition Identifiers:

AI-generated Review of “Therapeutic applications of ribozymes and riboswitches”:


"Therapeutic applications of ribozymes and riboswitches" Table Of Contents:

  • 1- Identification of regulatory RNA in bacterial genomes by genome-scale mapping of transcription start sites --
  • 2- Screening inhibitory potential of anti-HIV RT RNA aptamers --
  • 3- Design and evaluation of clinically relevant SOFA-HDV ribozymes targeting HIV RNA --
  • 4- Directing RNase P-mediated cleavage of target mRNAs by engineered external guide sequences in cultured cells --
  • 5- Design and analysis of hammerhead ribozyme activity against an artificial gene target --
  • 6- Knockdown strategies for the study of proprotein convertases and proliferation in prostate cancer cells --
  • 7- Use of tumor-targeting trans-splicing ribozyme for cancer treatment --
  • 8- Characterization of hairpin ribozyme reactions --
  • 9- Finding instances of riboswitches and ribozymes by homology search of structured RNA with infernal --
  • 10- Structure-based virtual screening for the identification of RNA- binding ligands --
  • 11- Probing riboswitch binding sites with molecular docking, focused libraries, and in-line probing assays --
  • 12- Discovery of small molecule modifiers of micrornas for the treatment of HCV infection --
  • 13- Bacterial flavin mononucleotide riboswitches as targets for flavin analogs --
  • 14- Construction and application of riboswitch-based sensors that detect metabolites within bacterial cells --
  • 15- Screening assays to identify artificial glmS ribozyme activators --
  • 16- Analysis of riboswitch structure and ligand binding using small-angle X-ray scattering (SAXS) --
  • 17- Use of SHAPE to select 2AP substitution sites for RNA-ligand interactions and dynamics studies --
  • 18- Cell internalization SELEX: In vitro selection for molecules that internalize into cells --
  • 19- DNA electronic switches based on analyte-responsive aptamers.

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