"The Role Of Complement Anaphylatoxins (C3a And C5a) In Non-Small Cell Lung Cancer (NSCLC): A Systematic Review" - Information and Links:

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  • Title: ➤  The Role Of Complement Anaphylatoxins (C3a And C5a) In Non-Small Cell Lung Cancer (NSCLC): A Systematic Review
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  • Internet Archive ID: osf-registrations-fkvq3-v1

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The effect of anaphylatoxins C3a and/or C5a in NSCLC has not been thoroughly studied yet. Even though, a few studies have reported promising outcomes, there is no systematic review about this subject. A demonstration of the outcomes from experimental studies (which use human cell lines) and clinical studies who reported anaphylatoxins levels might improve our understanding about this topic and raise the interest for further research. Furthermore, there are complement inhibitors both experimental and, in the market, that might provide new therapeutic options for these deadly neoplasms. The aim of this systematic review is to study whether the increased levels of complement anaphylatoxins create a protumoral inflammatory environment for NSCLC growth and metastasis. According to our knowledge this is the first systematic review about the forementioned subject.

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  • Added Date: 2025-06-06 18:01:08
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