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"Serum Lithium Levels: Ideal Time For Sample Collection! Are We Doing It Right?" and the language of the book is English.


“Serum Lithium Levels: Ideal Time For Sample Collection! Are We Doing It Right?” Metadata:

  • Title: ➤  Serum Lithium Levels: Ideal Time For Sample Collection! Are We Doing It Right?
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  • Language: English

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  • Internet Archive ID: pubmed-PMC4100432

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"Serum Lithium Levels: Ideal Time For Sample Collection! Are We Doing It Right?" Description:

The Internet Archive:

This article is from <a href="//archive.org/search.php?query=journaltitle%3A%28Indian%20Journal%20of%20Psychological%20Medicine%29" rel="nofollow">Indian Journal of Psychological Medicine</a>, <a href="//archive.org/search.php?query=journaltitle%3A%28Indian%20Journal%20of%20Psychological%20Medicine%29%20AND%20volume%3A%2836%29" rel="nofollow">volume 36</a>.<h2>Abstract</h2>Lithium has been the gold standard drug for bipolar disorders. The efficacy of lithium is dose-dependent and reliably correlates with that of serum lithium levels (trough levels). Trough levels are best measured when tested just before the next dose. In clinical practice, when lithium was administered in divided doses, trough levels were measured at 12 h after the last dose. Does this practice of 12 h lithium estimation apply to once a day (OD) administration of lithium also? This study was undertaken to test this hypothesis. Serum lithium levels were measured at 12 and 24 h post the last dose in 48 patients taking an OD dosing of sustained preparations of lithium. The mean and (standard deviation) of serum lithium levels at 12 h (0.82 [0.29]) and at 24 h (0.60 [0.20]) were calculated. The serum lithium level at 12 h was 1.3 times higher than that of the 24 h levels (actual trough levels). Thus, it seems appropriate to estimate the serum lithium levels (trough levels) at 24 h post the last dose in patients taking lithium as an OD dosage, which may prevent patient maintained on a lower than required dose of lithium.

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"Serum Lithium Levels: Ideal Time For Sample Collection! Are We Doing It Right?" is available for download from The Internet Archive in "texts" format, the size of the file-s is: 0.75 Mbs, and the file-s went public at Wed Oct 15 2014.

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  • Source: Internet Archive
  • Internet Archive Link: Archive.org page
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  • Number of Files: 6
  • Number of Available Files: 6
  • Added Date: 2014-10-15 21:37:41
  • Scanner: Internet Archive Python library 0.7.2

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