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  • Title: ➤  Response Inhibition In Children With Fragile X Syndrome And Autism
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  • Internet Archive ID: osf-registrations-pvwbj-v1

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Autism spectrum disorder (ASD) (hereafter: autism) is a neurodevelopmental condition that is characterized by social difficulties and restrictive and repetitive behaviors. Fragile X syndrome (FXS) is the most common single-gene cause of autism (Kidd et al., 2014; Lozano et al., 2016; Stone et al., 2024). Children with FXS and children with autism often display difficulties with executive functioning (Schmitt et al., 2007). One particular domain on which children with FXS (Sullivan et al., 2007; Tonnsen, 2016) and children with autism (Hlavatá et al., 2018) are known to have issues is response inhibition. In this study we aim to increase our understanding of the neurocognitive phenotype of children and adolescents with FXS or autism by comparing them with a typically developing (TD) group on their response inhibition capabilities. We will compare our groups on response inhibition using behavioral data from an inhibition task and the performance on a subtask of the NEPSY-II. In addition, we will explore group differences in pupil sizes during our inhibition task. It has been shown that pupil size increases during tasks that require cognitive control (e.g. a task requiring response inhibition), but also decrease as a task becomes too demanding and induces cognitive fatigue (Mahot, 2018). Therefore, comparing pupillometric data between our study groups can give us insights on the cognitive load demands of response inhibition children and adolescents with FXS or autism.

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  • Source: Internet Archive
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  • Number of Files: 5
  • Number of Available Files: 5
  • Added Date: 2025-06-16 11:00:23
  • Scanner: Internet Archive Python library 1.9.9

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