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  • Title: ➤  Protocol For A Systematic Scoping Review Of Applications Of Agreement Methods In The Health Sciences
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Agreement studies assess how well two or more instruments agree in their measurements of the same variable. There are multiple methods described for assessing agreement, but not all of them are appropriate. Our objectives are to determine which methods of analysing continuous agreement are currently being used in the health sciences literature and quantify the frequency of different continuous agreement methods published in peer reviewed journals since 2010. Secondary objectives include assessment of whether inappropriate methods are still being used to analyse agreement; and to identify how many agreement studies have pre-defined a clinically acceptable difference (if appropriate). Articles using a continuous agreement method to analyse data related to human participants will be included if they were published in English since 1st January 2010. The following literature databases will be searched: MEDLINE (via Ovid), EMBASE (via Ovid), Cochrane Library Trials database, Web of Science, and Scopus from 1st January 2010 to the present. Additional publications will be found using forward citation tracking of key papers describing agreement methods. Deduplication will be performed, and natural language processing methods used to facilitate article screening and perform data extraction in order to enhance efficiency of processing an estimated dataset of 150,000 papers. To provide a quality control check of the machine learning procedure, manual screening and data extraction will be performed on the subset of articles published in the asthma field. The results will be summarised via descriptive analyses. We will publish in peer reviewed journals, and present our findings at national and international conferences. In addition, public and patient representatives, and clinical and academic end users of agreement methods will advise on innovative dissemination strategies.

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