NASA Technical Reports Server (NTRS) 19910006360: The Rotating Spectrometer: New Biotechnology For Cell Separations - Info and Reading Options
By NASA Technical Reports Server (NTRS)
"NASA Technical Reports Server (NTRS) 19910006360: The Rotating Spectrometer: New Biotechnology For Cell Separations" and the language of the book is English.
“NASA Technical Reports Server (NTRS) 19910006360: The Rotating Spectrometer: New Biotechnology For Cell Separations” Metadata:
- Title: ➤ NASA Technical Reports Server (NTRS) 19910006360: The Rotating Spectrometer: New Biotechnology For Cell Separations
- Author: ➤ NASA Technical Reports Server (NTRS)
- Language: English
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- Internet Archive ID: NASA_NTRS_Archive_19910006360
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"NASA Technical Reports Server (NTRS) 19910006360: The Rotating Spectrometer: New Biotechnology For Cell Separations" Description:
The Internet Archive:
An instrument for biochemical studies, called the rotating spectrometer, separates previously inseparable cell cultures. The rotating spectrometer is intended for use in pharmacological studies which require fractional splitting of heterogeneous cell cultures based on cell morphology and swimming behavior. As a method to separate and concentrate cells in free solution, the rotating method requires active organism participation and can effectively split the large class of organisms known to form spontaneous patterns. Examples include the biochemical star, an organism called Tetrahymena pyriformis. Following focusing in a rotated frame, the separation is accomplished using different radial dependencies of concentrated algal and protozoan species. The focusing itself appears as concentric rings and arises from the coupling between swimming direction and Coriolis forces. A dense cut is taken at varying radii and extraction is replenished at an inlet. Unlike standard separation and concentrating techniques such as filtration or centrifugation, the instrument is able to separate motile from immotile fractions. For a single pass, typical split efficiencies can reach 200 to 300 percent compared to the inlet concentration.
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