Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials - Info and Reading Options
By John O'Quigley, Alexia Iasonos and Bjö Bornkamp
"Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials" was published by Taylor & Francis Group in 2017 - Milton, it has 306 pages and the language of the book is English.
“Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials” Metadata:
- Title: ➤ Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials
- Authors: John O'QuigleyAlexia IasonosBjö Bornkamp
- Language: English
- Number of Pages: 306
- Publisher: Taylor & Francis Group
- Publish Date: 2017
- Publish Location: Milton
“Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials” Subjects and Themes:
- Subjects: ➤ Drugs, dosage - Clinical trials - Drugs - Handbooks, manuals - Dose-response relationship - Statistical methods - Design - Dose-Response Relationship, Drug - Maximum Tolerated Dose - Phase I as Topic Clinical Trials - Methods - Phase II as Topic Clinical Trials - Drug Design - Médicaments - Guides, manuels - Relations dose-effet - Études cliniques - Méthodes statistiques - Conception - MEDICAL - Pharmacology
Edition Identifiers:
- The Open Library ID: OL33758046M - OL25192052W
- Online Computer Library Center (OCLC) ID: 985364216
- ISBN-13: 9781351648028
- All ISBNs: 9781351648028
AI-generated Review of “Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials”:
"Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials" Description:
Open Data:
Cover -- Half Title -- Title Page -- Copyright Page -- Contents -- Editors -- Preface -- Contributors -- I: Phase I designs -- 1 Overview of Phase I Designs -- 2 Model-Based Designs for Safety -- 3 Dose-Finding Methods for Nonbinary Outcomes -- 4 Dose-Finding Trials in Pediatric Oncology -- II: More advanced Phase I and Phase I/II methodology -- 5 Phase I/II Dose-Finding Designs with Efficacy and Safety Endpoints -- 6 Designing Early-Phase Drug Combination Trials -- 7 Dose-Schedule Finding in Early-Phase Clinical Trials -- 8 Patient Heterogeneity in Dose-Finding Trials -- 9 Nonparametric Optimal Design in Adaptive Dose-Finding Studies -- 10 Practical Implementation: Protocol Development -- III: Phase II Dose-Finding Trials -- 11 Dose-Finding Studies in Phase II: Introduction and Overview -- 12 The MCP-Mod Methodology: Practical Considerations and the DoseFinding R Package -- 13 Designing Phase II Dose-Finding Studies: Sample Size, Doses, and Dose Allocation Weights -- 14 Two-Stage Designs in Dose Finding -- 15 Longitudinal Dose-Response Models -- 16 Multiple Test Strategies for Comparing Several Doses with a Control in Confirmatory Trials -- 17 A Regulatory View on Dose-Finding Studies and on the Value of Dose-Exposure-Response Analysis -- Index
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