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"DTIC AD1037876: Adjustment Of The Severity Of Obstruction In Patients With Mixed Obstructive Restrictive Pulmonary Function Testing" and the language of the book is English.


“DTIC AD1037876: Adjustment Of The Severity Of Obstruction In Patients With Mixed Obstructive Restrictive Pulmonary Function Testing” Metadata:

  • Title: ➤  DTIC AD1037876: Adjustment Of The Severity Of Obstruction In Patients With Mixed Obstructive Restrictive Pulmonary Function Testing
  • Author: ➤  
  • Language: English

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  • Internet Archive ID: DTIC_AD1037876

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"DTIC AD1037876: Adjustment Of The Severity Of Obstruction In Patients With Mixed Obstructive Restrictive Pulmonary Function Testing" Description:

The Internet Archive:

The interpretation of a pulmonary function test (PFT) can be challenging in patients with mixed obstructive and restrictive disorders, especiall in regards to the degree of obstruction. Prior studies identified the FEV1 overestimates the degree of obstruction because FEV1 is reduced from both the obstructive and restrictive components of the underlying disease. One smaller study adjusted the FRV1 for the decrease in TLC to better define the severity of underlying airway obstruction, which resulted in 83% of patients being changed to a less severe grade of obstruction according to ATS/ERS guidelines. This study aims to evaluate a larger population of patients with a mixed obstructive-restrictive pattern on full PFTs in or to correlate the grade of obstruction based on the degree of restriction and underlying lung disease. METHODS: This study is a retrospective chart review of the PFT databases from multiple institutions. We selected individuals with both obstructive (FEV1/FVC less than lower limit of normal) and restrictive (TLC less than 80%) lung disease. The severity of obstruction for unadjusted (FEV1 % predicted alone) versus adjusted (FEV1 % predicted / TLC % predicted) values were compared and reported according to ATS/ERS guidelines. Additional comparisons were made based on the degree of restriction (less than 70% vs. less than 80%) and cause of underlying lung disease (COPD vs. other obstructive disease).

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  • Added Date: 2020-04-01 09:53:01
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