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1Study On The In Vivo Toxic Mechanism Of Xixin Based On Trace Elements Determination By Inductively Coupled Plasma-mass Spectrometry.

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This article is from Pharmacognosy Magazine , volume 10 . Abstract Background:: Xixin has been widely used as a traditional Chinese medicine for headache, toothache and inflammatory diseases. Clinical investigation indicated that adverse drug reactions occurred with an overdose of xixin, but the toxic mechanism of xixin in vivo based on trace elements has not been researched yet. Objective:: To explore the in vivo toxic mechanism of xixin induced by trace elements. Materials and Methods:: The contents of trace elements in the serum and liver of mice were determined by inductively coupled plasma-mass spectrometry (ICP-MS) after obtaining xixin extracts. Principal component analysis (PCA) and cluster analysis (CA) were performed between the trace elements’ content and dosage using the software GeneSpring 12.1 to analyze the main toxic elements in vivo. Results:: Trace elements’ contents were obviously raised after xixin extracts were taken as a dosage of 150 mg/mL and 50 mg/mL, respectively. Na, Ca, Cu and Cd in serum and Ca and Zn in liver were the main trace elements inducing the toxic reaction of xixin. Conclusion:: Xixin possesses the potential function of indirectly upregulating trace elements in vivo. This study, for the first time, elucidated the in vivo toxic mechanism of xixin based on trace elements. This method could also be utilized in the research of corresponding aspects.

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2Elements Of Mechanism: Elucidating The Scientific Principles Of The Practical Construction Of Machines, For The Use Of Schools, And Students In Mechanical Engineering, With Numerous Specimens Of Modern Machines, Remarkable For Their Utility And Ingenuity

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This article is from Pharmacognosy Magazine , volume 10 . Abstract Background:: Xixin has been widely used as a traditional Chinese medicine for headache, toothache and inflammatory diseases. Clinical investigation indicated that adverse drug reactions occurred with an overdose of xixin, but the toxic mechanism of xixin in vivo based on trace elements has not been researched yet. Objective:: To explore the in vivo toxic mechanism of xixin induced by trace elements. Materials and Methods:: The contents of trace elements in the serum and liver of mice were determined by inductively coupled plasma-mass spectrometry (ICP-MS) after obtaining xixin extracts. Principal component analysis (PCA) and cluster analysis (CA) were performed between the trace elements’ content and dosage using the software GeneSpring 12.1 to analyze the main toxic elements in vivo. Results:: Trace elements’ contents were obviously raised after xixin extracts were taken as a dosage of 150 mg/mL and 50 mg/mL, respectively. Na, Ca, Cu and Cd in serum and Ca and Zn in liver were the main trace elements inducing the toxic reaction of xixin. Conclusion:: Xixin possesses the potential function of indirectly upregulating trace elements in vivo. This study, for the first time, elucidated the in vivo toxic mechanism of xixin based on trace elements. This method could also be utilized in the research of corresponding aspects.

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  • Title: ➤  Elements Of Mechanism: Elucidating The Scientific Principles Of The Practical Construction Of Machines, For The Use Of Schools, And Students In Mechanical Engineering, With Numerous Specimens Of Modern Machines, Remarkable For Their Utility And Ingenuity
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3The Elements Of Mechanism

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359 p

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4At The Origin Of Spliceosomal Introns: Is Multiplication Of Introner-like Elements The Main Mechanism Of Intron Gain In Fungi?

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This article is from Communicative & Integrative Biology , volume 6 . Abstract The recent discovery of introner-like elements (ILEs) in six fungal species shed new light on the origin of regular spliceosomal introns (RSIs) and the mechanism of intron gains. These novel spliceosomal introns are found in hundreds of copies, are longer than RSIs and harbor stable predicted secondary structures. Yet, they are prone to degeneration in sequence and length to become undistinguishable from RSIs, suggesting that ILEs are predecessors of most RSIs. In most fungi, other near-identical introns were found duplicated in lower numbers in the same gene or in unrelated genes, indicating that intron duplication is a widespread phenomenon. However, ILEs are associated with the majority of intron gains, suggesting that the other types of duplication are of minor importance to the overall gains of introns. Our data support the hypothesis that ILEs’ multiplication corresponds to the main mechanism of intron gain in fungi.

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5Elements Of Electro-biology, Or The Voltaic Mechanism Of Man; Of Electro-pathology, Especially ...

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6The Elements Of Mechanism

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7Notes And Problems On The Elements Of Mechanism And The Transmission Of Power

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8Elements Of Electro-biology Or The Voltaic Mechanism Of Man [electronic Resource] : Of Electro-pathology, Especially Of The Nervous System ; And Of Electro- Therapeutics

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This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library

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9Principles Of The Human Mind Deduced From Physical Laws [electronic Resource] : Being A Sequel To Elements Of Electro-biology ; Together With The Lecture On The Voltaic Mechanism Of Man, Delivered At The London Institution, April 11, 1849

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This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library

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  • Language: English

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10The Elements Of Mechanism

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Book Source: Digital Library of India Item 2015.222045 dc.contributor.author: T M Goodeve dc.date.accessioned: 2015-07-09T22:33:02Z dc.date.available: 2015-07-09T22:33:02Z dc.date.digitalpublicationdate: 2005-04-17 dc.date.citation: 1885 dc.identifier.barcode: 2990150063248 dc.identifier.origpath: /data_copy/upload/0063/253 dc.identifier.copyno: 1 dc.identifier.uri: http://www.new.dli.ernet.in/handle/2015/222045 dc.description.scannerno: 50014 dc.description.scanningcentre: Salar Jung Museum dc.description.main: 1 dc.description.tagged: 0 dc.description.totalpages: 366 dc.format.mimetype: application/pdf dc.language.iso: English dc.publisher.digitalrepublisher: Digital Library Of India dc.publisher: Longmans Green And Co dc.source.library: Salar Jung Museum dc.subject.classification: Natural Sciences dc.subject.classification: Physics dc.title: The Elements Of Mechanism

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11The Elements Of Mechanism: Designed For Students Of Applied Mechanics

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12The Elements Of Mechanism: Designed For Students Of Applied Mechanics

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13Elements Of Physiology; Being Part I Of "The Human Mechanism: Its Physiology And Hygiene And The Sanitation Of Its Surroundings"

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14DTIC AD0020742: EFFECT OF ALLOYING ELEMENTS ON THE MECHANISM OF SULFUR TRANSFER ACROSS A SLAG-METAL INTERFACE--SILICON, MANGANESE, PHOSPHORUS, ALUMINUM, CARBON, NICKEL, COPPER

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The relative effectiveness of various alloy elements on the rate of S transfer was observed by the comparison of the rate constants for acid and basic slags. Of the elements studied, C, Si, Mn, and Al increased the rate of S transfer from Fe to C-saturated slag with increasing effectiveness in the order named. The data support a 3-stage mechanism where R=C, Si, Al or possibly Mn and M=Fe, Mn, or possibly Si.

“DTIC AD0020742: EFFECT OF ALLOYING ELEMENTS ON THE MECHANISM OF SULFUR TRANSFER ACROSS A SLAG-METAL INTERFACE--SILICON, MANGANESE, PHOSPHORUS, ALUMINUM, CARBON, NICKEL, COPPER” Metadata:

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  • Author: ➤  
  • Language: English

“DTIC AD0020742: EFFECT OF ALLOYING ELEMENTS ON THE MECHANISM OF SULFUR TRANSFER ACROSS A SLAG-METAL INTERFACE--SILICON, MANGANESE, PHOSPHORUS, ALUMINUM, CARBON, NICKEL, COPPER” Subjects and Themes:

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15DTIC AD0406074: STUDIES ON METABOLISM AND MECHANISM OF DESTRUCTION OF THE FORMED ELEMENTS OF THE BLOOD

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The relative effectiveness of various alloy elements on the rate of S transfer was observed by the comparison of the rate constants for acid and basic slags. Of the elements studied, C, Si, Mn, and Al increased the rate of S transfer from Fe to C-saturated slag with increasing effectiveness in the order named. The data support a 3-stage mechanism where R=C, Si, Al or possibly Mn and M=Fe, Mn, or possibly Si.

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16The Elements Of Mechanism

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17The Elements Of Mechanism

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18The Elements Of Mechanism

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19The Elements Of Mechanism

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14

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20The Elements Of Mechanism: Designed For Students Of Applied Mechanics

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21Elements Of Mechanism: Elucidating The Scientific Principles Of The Practical Construction Of ...

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22Industrial Drawing : Comprising The Description And Uses Of Drawing Instruments, The Construction Of Plane Figures, The Projections And Sections Of Geometrical Solids, Architectural Elements, Mechanism, And Topographical Drawing, With Remarks On The Method Of Teaching The Subject : For The Use Of Academies And Common Schools

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23The Elements Of Mechanism: Designed For Students Of Applied Mechanics

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24The Elements Of Mechanism

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25Elements Of Hygiene And Sanitation; Being Part II Of "The Human Mechanism: Its Physiology And Hygiene And The Sanitation Of Its Surroundings"

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[278] p

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26The Elements Of Mechanism

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27The Elements Of Mechanism: Designed For Students Of Applied Mechanics

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28The Elements Of Mechanism

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359 p

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29Elements Of Mechanism : Elucidating The Scientific Principles Of The Practical Construction Of Machines, For The Use Of Schools, And Students In Mechanical Engineering, With Numerous Specimens Of Modern Machines, Remarkable For Their Utility And Ingenuity

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30The Elements Of Mechanism

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31The Elements Of Mechanism

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32The Mechanism Of Core-Collapse Supernovae And The Ejection Of Heavy Elements

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We present here the first results of two-dimensional hydrodynamical simulations of the neutrino-heating phase in the collapsed core of a 15 solar mass star, where the neutrino transport is treated with a variable Eddington factor method for solving the Boltzmann transport equation, and the neutrino interactions include nucleon-nucleon bremsstrahlung, nucleon recoils and correlations, and weak-magnetism effects as well as direct interactions between neutrinos of different flavors. With the given input physics (neutrino reactions and nuclear equation of state), our best simulations do not develop strong convection in the neutrino-heating layer behind the shock and do not yield explosions. With about 30% higher neutrino-energy deposition behind the shock, however, an explosion occurs on a timescale of 150 ms after core bounce. It leaves behind a neutron star with an initial baryonic mass of 1.4 solar masses and ejects the N = 50 isotopes of Sr, Y and Zr in amounts consistent with Galactic abundances.

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33Elements Of Mechanism Elucidating The Scientist Principles Of The Practical Construction Of Machines By T. Baker

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We present here the first results of two-dimensional hydrodynamical simulations of the neutrino-heating phase in the collapsed core of a 15 solar mass star, where the neutrino transport is treated with a variable Eddington factor method for solving the Boltzmann transport equation, and the neutrino interactions include nucleon-nucleon bremsstrahlung, nucleon recoils and correlations, and weak-magnetism effects as well as direct interactions between neutrinos of different flavors. With the given input physics (neutrino reactions and nuclear equation of state), our best simulations do not develop strong convection in the neutrino-heating layer behind the shock and do not yield explosions. With about 30% higher neutrino-energy deposition behind the shock, however, an explosion occurs on a timescale of 150 ms after core bounce. It leaves behind a neutron star with an initial baryonic mass of 1.4 solar masses and ejects the N = 50 isotopes of Sr, Y and Zr in amounts consistent with Galactic abundances.

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34Industrial Drawing : Comprising The Description And Uses Of Drawing Instruments, The Construction Of Plane Figures, The Projections And Sections Of Geometrical Solids, Architectural Elements, Mechanism, And Topographical Drawing, With Remarks On The Method Of Teaching The Subject : For The Use Of Academies And Common Schools

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35Industrial Drawing, Comprising The Description And Uses Of Drawing Instruments, The Construction Of Plane Figures, The Projections And Sections Of Geometrical Solids; Architectural Elements, Mechanism, And Topographical Drawing, With Remarks On The Method Of Teaching The Subject

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52

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36The Elements Of Mechanism: Designed For Students Of Applied Mechanics

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37The Elements Of Mechanism

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38Elements Of Electro-biology, Or The Voltaic Mechanism Of Man; Or Electro-pathology, Especially Of The Nervous System; And Of Electro-therapeutics

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xii pages, 2 unnumbered leaves, 164 pages, 3 unnumbered leaves : (8vo)

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39A Small Organic Compound Enhances The Religation Reaction Of Human Topoisomerase I And Identifies Crucial Elements For The Religation Mechanism.

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This article is from Bioscience Reports , volume 33 . Abstract The different steps of the human Top1 (topoisomerase I) catalytic cycle have been analysed in the presence of a pentacyclic-diquinoid synthetic compound. The experiments indicate that it efficiently inhibits the cleavage step of the enzyme reaction, fitting well into the catalytic site. Surprisingly the compound, when incubated with the binary topoisomerase–DNA cleaved complex, helps the enzyme to remove itself from the cleaved DNA and close the DNA gap, increasing the religation rate. The compound also induces the religation of the stalled enzyme–CPT (camptothecin)–DNA ternary complex. Analysis of the molecule docked over the binary complex, together with its chemical properties, suggests that the religation enhancement is due to the presence on the compound of two oxygen atoms that act as hydrogen acceptors. This property facilitates the deprotonation of the 5′ DNA end, suggesting that this is the limiting step in the topoisomerase religation mechanism.

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40Elements Of Mechanism: Elucidating The Scientific Principles Of The ...

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41The Elements Of Mechanism

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345 p. : 19 cm

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1The elements of mechanism

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    1History of King Lear

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    The History of King Lear is an adaptation by Nahum Tate of William Shakespeare's King Lear. It first appeared in 1681, some seventy-five years after Shakespeare's version, and is believed to have replaced Shakespeare's version on the English stage in whole or in part until 1838. Unlike Shakespeare's tragedy, Tate's play has a happy ending, with Lear regaining his throne, Cordelia marrying Edgar, and Edgar joyfully declaring that "truth and virtue shall at last succeed." Regarded as a tragicomedy, the play has five acts, as does Shakespeare's, although the number of scenes is different, and the text is about eight hundred lines shorter than Shakespeare's. Many of Shakespeare's original lines are retained, or modified only slightly, but a significant portion of the text is entirely new, and much is omitted. The character of the Fool, for example, is absent. Although many critics — including Joseph Addison, August Wilhelm Schlegel, Charles Lamb, William Hazlitt, and Anna Jameson — condemned Tate's adaptation for what they saw as its cheap sentimentality, it was popular with theatregoers, and was approved by Samuel Johnson, who regarded Cordelia's death in Shakespeare's play as unbearable. Shakespeare's version continued to appear in printed editions of his works, but, according to numerous scholars, including A.C. Bradley and Stanley Wells, did not appear on the English stage for over a hundred and fifty years from the date of the first performance of Tate's play Actors such as Thomas Betterton, David Garrick, and John Philip Kemble, who were famous for the role of Lear, were portraying Tate's Lear, not Shakespeare's. (Summary by Wikipedia) <br/><br/><strong>Cast</strong><br>King Lear: <a href="http://librivox.org/reader/6446">Bob Gonzalez</a><br>Gloster: <a href="http://librivox.org/reader/3595">Martin Geeson</a><br>Kent: <a href="http://librivox.org/reader/3536">Arielle Lipshaw</a><br>Edgar: <a href="http://librivox.org/reader/6553">Dublin Gothic</a><br>Edmund, the Bastard: <a href="http://librivox.org/reader/1259">Elizabeth Klett</a><br>Cornwall: <a href="http://librivox.org/reader/5141">David Goldfarb</a><br>Cornwall's Servant/Old Man/Gentleman/Servant: <a href="http://librivox.org/reader/4705">Algy Pug</a><br>Albany: <a href="http://librivox.org/reader/6965">Noel Badrian</a><br>Burgundy/Physician: <a href="http://librivox.org/reader/7010">VikingJames</a><br>Goneril's gentleman: <a href="http://librivox.org/reader/6548">Kristingj</a><br>Attendant/Messenger: <a href="http://librivox.org/reader/7233">CJacobA</a><br>Arante/Herald: <a href="http://librivox.org/reader/6689">Tiffany Halla Colonna</a><br>First Ruffian/Officer: <a href="http://librivox.org/reader/7122">Nathaniel W. C. Higgins</a><br>Second Ruffian/Captain: <a href="http://librivox.org/reader/7247">Robert Hoffman</a><br>Gonerill: <a href="http://librivox.org/reader/3816">Bev J. Stevens</a><br>Regan: <a href="http://librivox.org/reader/6147">Liberty Stump</a><br>Cordelia: <a href="http://librivox.org/reader/5017">Miss Avarice</a><br>Narrator: <a href="http://librivox.org/reader/4705">Algy Pug</a><br>Introduction/Prologue/Dramatis Personae: <a href="http://librivox.org/reader/3595">Martin Geeson</a><br><br><strong>Audio edited by Phil Chenevert</strong>

    “History of King Lear” Metadata:

    • Title: History of King Lear
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    • Language: English
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    • Format: Audio
    • Number of Sections: 24
    • Total Time: 2:38:49

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    • File Name: historyofkinglear_1208_librivox
    • File Format: zip
    • Total Time: 2:38:49
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    2Dido and Aeneas

    By

    Nahum Tate wrote this libretto to be set to music by Henry Purcell. It was first performed in 1689 and has become one of the most popular works in the Early Opera repertoire. For this recording the Prologue is read by a single narrator while the 3 Acts of the opera are dramatised in a spoken-word version. <br><br> The story is taken from Book IV of Virgil's Aeneid and relates the intense but ultimately tragic love affair between Dido, Queen of Carthage, and Aeneas, a survivor of the destruction of Troy who has been charged by the Gods with the task of travelling to Italy to found Rome. <br><br> (Summary by Alan Mapstone) <br><br> Cast of Characters: <br> Dido, Queen of Carthage: <a href="https://librivox.org/reader/17662">Inkell</a><br> Aeneas, a Trojan: <a href="https://librivox.org/reader/18171">Mathias Thorndal</a><br> Belinda: <a href="https://librivox.org/reader/3157">TriciaG</a><br> Woman attendant on Queen Dido: <a href="https://librivox.org/reader/6924">Rapunzelina</a><br> Sorceress: <a href="https://librivox.org/reader/10248">Estefanía Vidal</a><br> Inchantress: <a href="https://librivox.org/reader/10179">Sonia</a><br> Chorus: <a href="https://librivox.org/reader/17576">Beeswaxcandle</a><br> Narration: <a href="https://librivox.org/reader/7170">Alan Mapstone</a><br>

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    • Title: Dido and Aeneas
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    • Language: English
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    • Format: Audio
    • Number of Sections: 4
    • Total Time: 00:20:23

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    • File Name: dido_aeneas_dr_2304_librivox
    • File Format: zip
    • Total Time: 00:20:23
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