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Pulmonary Function Testing by Jack Wanger

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1Equivalence Testing For Functional Data With An Application To Comparing Pulmonary Function Devices

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Equivalence testing for scalar data has been well addressed in the literature, however, the same cannot be said for functional data. The resultant complexity from maintaining the functional structure of the data, rather than using a scalar transformation to reduce dimensionality, renders the existing literature on equivalence testing inadequate for the desired inference. We propose a framework for equivalence testing for functional data within both the frequentist and Bayesian paradigms. This framework combines extensions of scalar methodologies with new methodology for functional data. Our frequentist hypothesis test extends the Two One-Sided Testing (TOST) procedure for equivalence testing to the functional regime. We conduct this TOST procedure through the use of the nonparametric bootstrap. Our Bayesian methodology employs a functional analysis of variance model, and uses a flexible class of Gaussian Processes for both modeling our data and as prior distributions. Through our analysis, we introduce a model for heteroscedastic variances within a Gaussian Process by modeling variance curves via Log-Gaussian Process priors. We stress the importance of choosing prior distributions that are commensurate with the prior state of knowledge and evidence regarding practical equivalence. We illustrate these testing methods through data from an ongoing method comparison study between two devices for pulmonary function testing. In so doing, we provide not only concrete motivation for equivalence testing for functional data, but also a blueprint for researchers who hope to conduct similar inference.

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2Paediatric Functional Lung Imaging And Pulmonary Function Testing: A Scoping Review

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Protocol for scoping review of functional lung imaging in paediatrics and how these modalities have been compared to pulmonary function tests

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3Manual Of Pulmonary Function Testing

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Protocol for scoping review of functional lung imaging in paediatrics and how these modalities have been compared to pulmonary function tests

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The book is available for download in "texts" format, the size of the file-s is: 1398.35 Mbs, the file-s for this book were downloaded 32 times, the file-s went public at Thu Jan 10 2019.

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4Pulmonary Function Testing : Indications And Interpretations : A Project Of The California Thoracic Society

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Protocol for scoping review of functional lung imaging in paediatrics and how these modalities have been compared to pulmonary function tests

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The book is available for download in "texts" format, the size of the file-s is: 1170.60 Mbs, the file-s for this book were downloaded 16 times, the file-s went public at Sun Dec 02 2018.

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5Manual Of Pulmonary Function Testing

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Protocol for scoping review of functional lung imaging in paediatrics and how these modalities have been compared to pulmonary function tests

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The book is available for download in "texts" format, the size of the file-s is: 1343.65 Mbs, the file-s for this book were downloaded 77 times, the file-s went public at Fri Dec 27 2019.

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6DTIC AD1037876: Adjustment Of The Severity Of Obstruction In Patients With Mixed Obstructive Restrictive Pulmonary Function Testing

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The interpretation of a pulmonary function test (PFT) can be challenging in patients with mixed obstructive and restrictive disorders, especiall in regards to the degree of obstruction. Prior studies identified the FEV1 overestimates the degree of obstruction because FEV1 is reduced from both the obstructive and restrictive components of the underlying disease. One smaller study adjusted the FRV1 for the decrease in TLC to better define the severity of underlying airway obstruction, which resulted in 83% of patients being changed to a less severe grade of obstruction according to ATS/ERS guidelines. This study aims to evaluate a larger population of patients with a mixed obstructive-restrictive pattern on full PFTs in or to correlate the grade of obstruction based on the degree of restriction and underlying lung disease. METHODS: This study is a retrospective chart review of the PFT databases from multiple institutions. We selected individuals with both obstructive (FEV1/FVC less than lower limit of normal) and restrictive (TLC less than 80%) lung disease. The severity of obstruction for unadjusted (FEV1 % predicted alone) versus adjusted (FEV1 % predicted / TLC % predicted) values were compared and reported according to ATS/ERS guidelines. Additional comparisons were made based on the degree of restriction (less than 70% vs. less than 80%) and cause of underlying lung disease (COPD vs. other obstructive disease).

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7Development And Evaluation Of An Improved Technique For Pulmonary Function Testing Using Electrical Impedance Pneumography Intended For The Diagnosis Of Chronic Obstructive Pulmonary Disease Patients.

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This article is from Sensors (Basel, Switzerland) , volume 13 . Abstract Spirometry is regarded as the only effective method for detecting pulmonary function test (PFT) indices. In this study, a novel impedance pulmonary function measurement system (IPFS) is developed for directly assessing PFT indices. IPFS can obtain high resolution values and remove motion artifacts through real-time base impedance feedback. Feedback enables the detection of PFT indices using only both hands for convenience. IPFS showed no differences in the sitting, supine, and standing postures during the measurements, indicating that patient posture has no effect on IPFS. Mean distance analysis showed good agreement between the volume and flow signal of IPFS (p < 0.05). PFT indices were detected in subjects to differentiate a chronic obstructive pulmonary disease (COPD) patient group from a normal group. The forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), FEV1/FVC, and peak expiratory flow (PEF) in the COPD group were lower than those in the normal group by IPFS (p < 0.05). IPFS is therefore suitable for evaluating pulmonary function in normal and COPD patients. Moreover, IPFS could be useful for periodic monitoring of existing patients diagnosed with obstructive lung disease.

“Development And Evaluation Of An Improved Technique For Pulmonary Function Testing Using Electrical Impedance Pneumography Intended For The Diagnosis Of Chronic Obstructive Pulmonary Disease Patients.” Metadata:

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The book is available for download in "texts" format, the size of the file-s is: 11.50 Mbs, the file-s for this book were downloaded 63 times, the file-s went public at Wed Oct 29 2014.

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8Pulmonary Function Testing In Children: Techniques And Standards

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ix, 273 pages : 27 cm

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9Pulmonary Function Testing : A Practical Approach

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ix, 273 pages : 27 cm

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10Elevation Of 1-Hour Plasma Glucose During Oral Glucose Tolerance Testing Is Associated With Worse Pulmonary Function In Cystic Fibrosis.

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This article is from Diabetes Care , volume 34 . Abstract OBJECTIVE: Cystic fibrosis (CF)-related diabetes (CFRD) is associated with declining pulmonary function and increased mortality. During oral glucose tolerance testing (OGTT), CFRD is defined by 2-h plasma glucose (PG2). We hypothesized PG elevations during OGTT resolving by 2 h, not meeting CFRD criteria, influence pulmonary function in CF. Thus we investigated the frequency of elevated 1-h OGTT PG (PG1) and its relationship with pulmonary function. RESEARCH DESIGN AND METHODS: Retrospective review of OGTTs was performed between August 2005 (annual screening initiation) and June 2008 at Children’s Hospital of Philadelphia CF Center. First-time, well state OGTTs (PG0, PG1, PG2) were analyzed. Additional data collected were: percent predicted forced expiratory volume in 1 s (FEV1), BMI percentile, lung bacterial colonization, age, and sex. OGTTs were categorized as normal (PG2

“Elevation Of 1-Hour Plasma Glucose During Oral Glucose Tolerance Testing Is Associated With Worse Pulmonary Function In Cystic Fibrosis.” Metadata:

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11Pulmonary Function Testing : A Practical Approach

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This article is from Diabetes Care , volume 34 . Abstract OBJECTIVE: Cystic fibrosis (CF)-related diabetes (CFRD) is associated with declining pulmonary function and increased mortality. During oral glucose tolerance testing (OGTT), CFRD is defined by 2-h plasma glucose (PG2). We hypothesized PG elevations during OGTT resolving by 2 h, not meeting CFRD criteria, influence pulmonary function in CF. Thus we investigated the frequency of elevated 1-h OGTT PG (PG1) and its relationship with pulmonary function. RESEARCH DESIGN AND METHODS: Retrospective review of OGTTs was performed between August 2005 (annual screening initiation) and June 2008 at Children’s Hospital of Philadelphia CF Center. First-time, well state OGTTs (PG0, PG1, PG2) were analyzed. Additional data collected were: percent predicted forced expiratory volume in 1 s (FEV1), BMI percentile, lung bacterial colonization, age, and sex. OGTTs were categorized as normal (PG2

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12NASA Technical Reports Server (NTRS) 19760024847: An Automated System For Pulmonary Function Testing

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An experiment to quantitate pulmonary function was accepted for the space shuttle concept verification test. The single breath maneuver and the nitrogen washout are combined to reduce the test time. Parameters are defined from the forced vital capacity maneuvers. A spirometer measures the breath volume and a magnetic section mass spectrometer provides definition of gas composition. Mass spectrometer and spirometer data are analyzed by a PDP-81 digital computer.

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13DTIC ADA018067: Pulmonary Function Testing In Military Personnel: A Preliminary Study,

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The military community is made up of a very diverse group of individuals representing a random sample from all walks of life and geographical locations. Although these individuals are supposedly healthy, an increasing number of them are later being diagnosed as having obstructive ventilatory mechanics. This study is concerned with the pulmonary function results of a supposedly healthy population of Naval Aviation Officer Candidates and designated Naval Aviators at Naval Air Station, Pensacola, Florida. The data suggest a high incidence of obstructive ventilatory mechanics in a relatively young age group (20-24 years old). Whereas most studies such as this reflect disease statistics in patients already symptomatic, this current investigation reveals a significant percentage (23.5%) of the as yet asymptomatic young age group who have the beginnings of a long-term process. (Author)

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14Occupational Health Surveillance: Pulmonary Function Testing In Emergency Responders.

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This article is from Journal of Emergencies, Trauma, and Shock , volume 7 . Abstract Emergency responders may be exposed to a variety of fumes, gases, and particulates during the course of their job that can affect pulmonary function (PF) and require the use of respiratory protection. This investigation used occupational health monitoring examination data to characterize PF in a population currently employed as emergency responders. PF tests for workers who required health examinations to ensure fitness for continued respirator use were compared to the National Health and Nutrition Examination Survey (NHANES) III Raw Spirometry database to determine if decreased PF was associated with employment as an emergency responder. The results of this research indicated that the emergency responders experienced a modest, but statistically significant, increase in forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) mean values over the NHANES III population in both total and stratified analyses, including stratification by age, gender, height, and smoking history. Results are likely due to a combination of effectively controlled exposures in the workplace, and the healthy worker effect among long-term workers. PF testing required by the Occupational and Safety Health Administration (OSHA) has substantial utility for conducting occupational surveillance at the population level. In this investigation, we were able to quickly evaluate if abnormal PF existed in an industrial sector known to have exposures that, when uncontrolled, can lead to PF impairment.

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1517. Physiology Respiration Expiration, Lung Compliance, Pulmonary Function Testing

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16Paediatric Pulmonary Function Testing

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17Manual Of Pulmonary Function Testing

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18Pulmonary Function Testing

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19Pulmonary Function Testing Guidelines And Controversies : Equipment, Methods, And Normal Values

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  • Title: ➤  Pulmonary Function Testing Guidelines And Controversies : Equipment, Methods, And Normal Values
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20Proficiency Laboratory Manual To Accompany Pulmonary Function Testing And Cardiopulmonary Stress Testing

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  • Title: ➤  Proficiency Laboratory Manual To Accompany Pulmonary Function Testing And Cardiopulmonary Stress Testing
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21Pulmonary Function Testing & Interpretation

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22Manual Of Pulmonary Function Testing

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  • Title: ➤  Manual Of Pulmonary Function Testing
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The book is available for download in "texts" format, the size of the file-s is: 1518.28 Mbs, the file-s for this book were downloaded 75 times, the file-s went public at Mon Nov 26 2018.

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23Manual Of Pulmonary Function Testing

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The book is available for download in "texts" format, the size of the file-s is: 1173.17 Mbs, the file-s for this book were downloaded 151 times, the file-s went public at Mon Nov 30 2020.

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24DTIC ADA029138: Pulmonary Function Testing In Aviation Selectees,

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Aviation students were divided into four groups and pulmonary function tests results compared among nonsmokers, former smokers, current smokers, and those with pulmonary symptoms. Cigarette smoking did not have any measurable effect on pulmonary functions. Pulmonary functions for the purpose of establishing norms for this age group according to height are summarized.

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  • Title: ➤  DTIC ADA029138: Pulmonary Function Testing In Aviation Selectees,
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  • Language: English

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The book is available for download in "texts" format, the size of the file-s is: 5.51 Mbs, the file-s for this book were downloaded 83 times, the file-s went public at Fri Nov 06 2015.

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25Pulmonary Function Testing And Cardiopulmonary Stress Testing

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Aviation students were divided into four groups and pulmonary function tests results compared among nonsmokers, former smokers, current smokers, and those with pulmonary symptoms. Cigarette smoking did not have any measurable effect on pulmonary functions. Pulmonary functions for the purpose of establishing norms for this age group according to height are summarized.

“Pulmonary Function Testing And Cardiopulmonary Stress Testing” Metadata:

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The book is available for download in "texts" format, the size of the file-s is: 1493.56 Mbs, the file-s for this book were downloaded 84 times, the file-s went public at Tue Nov 16 2021.

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26Pulmonary Function Testing And Cardiopulmonary Stress Testing

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Aviation students were divided into four groups and pulmonary function tests results compared among nonsmokers, former smokers, current smokers, and those with pulmonary symptoms. Cigarette smoking did not have any measurable effect on pulmonary functions. Pulmonary functions for the purpose of establishing norms for this age group according to height are summarized.

“Pulmonary Function Testing And Cardiopulmonary Stress Testing” Metadata:

  • Title: ➤  Pulmonary Function Testing And Cardiopulmonary Stress Testing
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  • Language: English

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The book is available for download in "texts" format, the size of the file-s is: 1289.70 Mbs, the file-s for this book were downloaded 34 times, the file-s went public at Tue Jan 25 2022.

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27Pneumomediastinum, Subcutaneous Emphysema, And Pneumothorax After A Pulmonary Function Testing In A Patient With Bleomycin-induced Interstitial Pneumonitis*.

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This article is from Jornal Brasileiro de Pneumologia : Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia , volume 39 . Abstract Spontaneous pneumomediastinum is an uncommon event, the clinical picture of which includes retrosternal chest pain, subcutaneous emphysema, dyspnea, and dysphonia. The pathophysiological mechanism involved is the emergence of a pressure gradient between the alveoli and surrounding structures, causing alveolar rupture with subsequent dissection of the peribronchovascular sheath and infiltration of the mediastinum and subcutaneous tissue with air. Known triggers include acute exacerbations of asthma and situations that require the Valsalva maneuver. We described and documented with HRCT scans the occurrence of pneumomediastinum after a patient with bleomycin-induced interstitial lung disease underwent pulmonary function testing. Although uncommon, the association between pulmonary function testing and air leak syndromes has been increasingly reported in the literature, and lung diseases, such as interstitial lung diseases, include structural changes that facilitate the occurrence of this complication.

“Pneumomediastinum, Subcutaneous Emphysema, And Pneumothorax After A Pulmonary Function Testing In A Patient With Bleomycin-induced Interstitial Pneumonitis*.” Metadata:

  • Title: ➤  Pneumomediastinum, Subcutaneous Emphysema, And Pneumothorax After A Pulmonary Function Testing In A Patient With Bleomycin-induced Interstitial Pneumonitis*.
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  • Language: English

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The book is available for download in "texts" format, the size of the file-s is: 5.83 Mbs, the file-s for this book were downloaded 72 times, the file-s went public at Thu Oct 16 2014.

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