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In Vitro Methods In Toxicology by C. K. Atterwill

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1In Vitro Methods Of Toxicology

“In Vitro Methods Of Toxicology” Metadata:

  • Title: In Vitro Methods Of Toxicology
  • Language: English

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The book is available for download in "texts" format, the size of the file-s is: 805.02 Mbs, the file-s for this book were downloaded 15 times, the file-s went public at Sat Jun 29 2019.

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2In Vitro Methods In Toxicology

“In Vitro Methods In Toxicology” Metadata:

  • Title: In Vitro Methods In Toxicology
  • Language: English

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The book is available for download in "texts" format, the size of the file-s is: 1306.24 Mbs, the file-s for this book were downloaded 31 times, the file-s went public at Thu May 28 2020.

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3In Vitro Methods In Developmental Toxicology : Use In Defining Mechanisms And Risk Parameters

“In Vitro Methods In Developmental Toxicology : Use In Defining Mechanisms And Risk Parameters” Metadata:

  • Title: ➤  In Vitro Methods In Developmental Toxicology : Use In Defining Mechanisms And Risk Parameters
  • Language: English

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The book is available for download in "texts" format, the size of the file-s is: 415.33 Mbs, the file-s for this book were downloaded 22 times, the file-s went public at Fri Oct 09 2020.

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4In Vitro Toxicology : Model Systems And Methods

“In Vitro Toxicology : Model Systems And Methods” Metadata:

  • Title: ➤  In Vitro Toxicology : Model Systems And Methods
  • Language: English

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The book is available for download in "texts" format, the size of the file-s is: 605.58 Mbs, the file-s for this book were downloaded 18 times, the file-s went public at Wed May 27 2020.

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5In Vitro Methods In Toxicology

“In Vitro Methods In Toxicology” Metadata:

  • Title: In Vitro Methods In Toxicology
  • Language: English

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The book is available for download in "texts" format, the size of the file-s is: 746.60 Mbs, the file-s for this book were downloaded 19 times, the file-s went public at Fri May 21 2021.

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6In Vitro Methods Of Toxicology

“In Vitro Methods Of Toxicology” Metadata:

  • Title: In Vitro Methods Of Toxicology
  • Language: English

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The book is available for download in "texts" format, the size of the file-s is: 709.19 Mbs, the file-s for this book were downloaded 23 times, the file-s went public at Thu May 28 2020.

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7Predictive Toxicology Of Cobalt Ferrite Nanoparticles: Comparative In-vitro Study Of Different Cellular Models Using Methods Of Knowledge Discovery From Data.

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This article is from Particle and Fibre Toxicology , volume 10 . Abstract Background: Cobalt-ferrite nanoparticles (Co-Fe NPs) are attractive for nanotechnology-based therapies. Thus, exploring their effect on viability of seven different cell lines representing different organs of the human body is highly important. Methods: The toxicological effects of Co-Fe NPs were studied by in-vitro exposure of A549 and NCIH441 cell-lines (lung), precision-cut lung slices from rat, HepG2 cell-line (liver), MDCK cell-line (kidney), Caco-2 TC7 cell-line (intestine), TK6 (lymphoblasts) and primary mouse dendritic-cells. Toxicity was examined following exposure to Co-Fe NPs in the concentration range of 0.05 -1.2 mM for 24 and 72 h, using Alamar blue, MTT and neutral red assays. Changes in oxidative stress were determined by a dichlorodihydrofluorescein diacetate based assay. Data analysis and predictive modeling of the obtained data sets were executed by employing methods of Knowledge Discovery from Data with emphasis on a decision tree model (J48). Results: Different dose–response curves of cell viability were obtained for each of the seven cell lines upon exposure to Co-Fe NPs. Increase of oxidative stress was induced by Co-Fe NPs and found to be dependent on the cell type. A high linear correlation (R2=0.97) was found between the toxicity of Co-Fe NPs and the extent of ROS generation following their exposure to Co-Fe NPs. The algorithm we applied to model the observed toxicity belongs to a type of supervised classifier. The decision tree model yielded the following order with decrease of the ranking parameter: NP concentrations (as the most influencing parameter), cell type (possessing the following hierarchy of cell sensitivity towards viability decrease: TK6 > Lung slices > NCIH441 > Caco-2 = MDCK > A549 > HepG2 = Dendritic) and time of exposure, where the highest-ranking parameter (NP concentration) provides the highest information gain with respect to toxicity. The validity of the chosen decision tree model J48 was established by yielding a higher accuracy than that of the well-known “naive bayes” classifier. Conclusions: The observed correlation between the oxidative stress, caused by the presence of the Co-Fe NPs, with the hierarchy of sensitivity of the different cell types towards toxicity, suggests that oxidative stress is one possible mechanism for the toxicity of Co-Fe NPs.

“Predictive Toxicology Of Cobalt Ferrite Nanoparticles: Comparative In-vitro Study Of Different Cellular Models Using Methods Of Knowledge Discovery From Data.” Metadata:

  • Title: ➤  Predictive Toxicology Of Cobalt Ferrite Nanoparticles: Comparative In-vitro Study Of Different Cellular Models Using Methods Of Knowledge Discovery From Data.
  • Authors: ➤  
  • Language: English

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The book is available for download in "texts" format, the size of the file-s is: 29.74 Mbs, the file-s for this book were downloaded 93 times, the file-s went public at Tue Oct 28 2014.

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1In vitro methods in toxicology

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“In vitro methods in toxicology” Metadata:

  • Title: In vitro methods in toxicology
  • Authors:
  • Language: English
  • Number of Pages: Median: 458
  • Publisher: Cambridge University Press
  • Publish Date:
  • Publish Location: Cambridge - New York

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  • First Year Published: 1987
  • Is Full Text Available: Yes
  • Is The Book Public: No
  • Access Status: Borrowable

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