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Dtic Ada410583%3a Application Of Multiobjective Genetic Algorithms In Anatomy Based Dose Optimization In Brachytherapy And Its Comparation With Deterministic Algorithms by Defense Technical Information Center
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1DTIC ADA410583: Application Of Multiobjective Genetic Algorithms In Anatomy Based Dose Optimization In Brachytherapy And Its Comparation With Deterministic Algorithms
By Defense Technical Information Center
In High Dose Rate (HDR) brachytherapy the conventional dose optimization algorithms consider the multiple objectives in the form of an aggregate function which combines individual objectives into a single utility value, As a result, the optimization problem becomes single objective, prior to optimization. Up to 300 parameters must be optimized satisfying objectives which are often competing. We use multiobjective dose optimization methods where the objectives are expressed in terms of quantities derived from dose-volume histograms or in terms of statistical parameters of dose distributions from a small number of sampling points. For the last approach we compare the optimization results of evolutionary multiobjective algorithms with deterministic optimization methods. The deterministic algorithms are very efficient and produce the best results, but they also have the certain limitations. The performance of the multiobjective evolutionary algorithms is improved if a small part of the population is initialized by deterministic algorithms.
“DTIC ADA410583: Application Of Multiobjective Genetic Algorithms In Anatomy Based Dose Optimization In Brachytherapy And Its Comparation With Deterministic Algorithms” Metadata:
- Title: ➤ DTIC ADA410583: Application Of Multiobjective Genetic Algorithms In Anatomy Based Dose Optimization In Brachytherapy And Its Comparation With Deterministic Algorithms
- Author: ➤ Defense Technical Information Center
- Language: English
“DTIC ADA410583: Application Of Multiobjective Genetic Algorithms In Anatomy Based Dose Optimization In Brachytherapy And Its Comparation With Deterministic Algorithms” Subjects and Themes:
- Subjects: ➤ DTIC Archive - Milickovic, Natasa B - STADISCHE KLINIKEN OFFENENBACH (GERMANY) - *OPTIMIZATION - *DOSE RATE - ALGORITHMS - GERMANY - THERAPY - CANCER - GREECE
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- Internet Archive ID: DTIC_ADA410583
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The book is available for download in "texts" format, the size of the file-s is: 6.38 Mbs, the file-s for this book were downloaded 77 times, the file-s went public at Sat May 12 2018.
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