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Dtic Ada346327%3a Acoustic Microsensors Iii. Direct Detection Of Staphylococcal Enterotoxin B Employing A Piezoelectric Crystal Immunosensor With A Flexible Carboxylated Dextran Matrix As The Biochemical Interface. by Defense Technical Information Center

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1DTIC ADA346327: Acoustic Microsensors III. Direct Detection Of Staphylococcal Enterotoxin B Employing A Piezoelectric Crystal Immunosensor With A Flexible Carboxylated Dextran Matrix As The Biochemical Interface.

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Within the framework of the project 'Acoustic Microsensors' (A93KL448) the possibilities of a biosensor system based on an immunological reaction on a piezoelectric crystal sensor are investigated at the TNO Prins Maurits Laboratory (TNO-PML). The results described are a continuation of previous reported work in which the toxin Staphylococcal Enterotoxin B (SEB) was detected in a competition assay with a preincubation period of at least 20 minutes and a detection limit of 100 ng/ml. A new biochemical interface based on a flexible carboxylated dextran matrix, to which antibodies are bound, was developed. With this biosensor system SEB could be detected directly without a preincubation step at a lowest concentration of approximately 7 ng/ml. The biosensor can be easily regenerated by a one-minute injection of 0.1 M HCl.

“DTIC ADA346327: Acoustic Microsensors III. Direct Detection Of Staphylococcal Enterotoxin B Employing A Piezoelectric Crystal Immunosensor With A Flexible Carboxylated Dextran Matrix As The Biochemical Interface.” Metadata:

  • Title: ➤  DTIC ADA346327: Acoustic Microsensors III. Direct Detection Of Staphylococcal Enterotoxin B Employing A Piezoelectric Crystal Immunosensor With A Flexible Carboxylated Dextran Matrix As The Biochemical Interface.
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  • Language: English

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The book is available for download in "texts" format, the size of the file-s is: 13.14 Mbs, the file-s for this book were downloaded 45 times, the file-s went public at Mon Apr 16 2018.

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