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This is the second edition of the Air Force Design Manual, Design of Protective Structures to Resist the Effects of Nuclear Weapons, AFSWC TR-59-70. Its intended use is for the planning and design of structures to resist the effects of nuclear weapons ranging into the megaton class. The emphasis is primarily on underground construction. The material presented is derived from existing knowledge and theory, so that the manual is also a report of the state of the art. Starting with general considerations of site selection and structural function, various phases of design are considered: free field phenomena in air and ground, material properties, failure criteria, architectural and mechanical features, radiation effects, surface openings, conversion of free-field phenomena to loads on structures, and the design and proportion of structural elements and structures.