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This is the first report on extended distribution of C. razianum K.G.Bhat in the Western Ghats region of Karnataka. The floristic composition the area (Charmady Ghat region) in which Combretum razianum is growing was carried out. The regeneration of this species was found to be very poor.

This is the first report on extended distribution of C. razianum K.G.Bhat in the Western Ghats region of Karnataka. The floristic composition the area (Charmady Ghat region) in which Combretum razianum is growing was carried out. The regeneration of this species was found to be very poor.

This is the first report on extended distribution of C. razianum K.G.Bhat in the Western Ghats region of Karnataka. The floristic composition the area (Charmady Ghat region) in which Combretum razianum is growing was carried out. The regeneration of this species was found to be very poor.

This is the first report on extended distribution of C. razianum K.G.Bhat in the Western Ghats region of Karnataka. The floristic composition the area (Charmady Ghat region) in which Combretum razianum is growing was carried out. The regeneration of this species was found to be very poor.

This is the first report on extended distribution of C. razianum K.G.Bhat in the Western Ghats region of Karnataka. The floristic composition the area (Charmady Ghat region) in which Combretum razianum is growing was carried out. The regeneration of this species was found to be very poor.

This is the first report on extended distribution of C. razianum K.G.Bhat in the Western Ghats region of Karnataka. The floristic composition the area (Charmady Ghat region) in which Combretum razianum is growing was carried out. The regeneration of this species was found to be very poor.

This is the first report on extended distribution of C. razianum K.G.Bhat in the Western Ghats region of Karnataka. The floristic composition the area (Charmady Ghat region) in which Combretum razianum is growing was carried out. The regeneration of this species was found to be very poor.

This is the first report on extended distribution of C. razianum K.G.Bhat in the Western Ghats region of Karnataka. The floristic composition the area (Charmady Ghat region) in which Combretum razianum is growing was carried out. The regeneration of this species was found to be very poor.

This is the first report on extended distribution of C. razianum K.G.Bhat in the Western Ghats region of Karnataka. The floristic composition the area (Charmady Ghat region) in which Combretum razianum is growing was carried out. The regeneration of this species was found to be very poor.

Source File: Department of Museums, Government of Tamil Nadu, Book 314

Source File: Department of Museums, Government of Tamil Nadu, Book 314

Source File: Department of Museums, Government of Tamil Nadu, Book 314

Source File: Department of Museums, Government of Tamil Nadu, Book 314

Source File: Department of Museums, Government of Tamil Nadu, Book 314

Source File: Department of Museums, Government of Tamil Nadu, Book 314

Source File: Department of Museums, Government of Tamil Nadu, Book 314

Source File: Department of Museums, Government of Tamil Nadu, Book 314

Source File: Department of Museums, Government of Tamil Nadu, Book 314

Source File: Department of Museums, Government of Tamil Nadu, Book 314

Source File: Department of Museums, Government of Tamil Nadu, Book 314

Source File: Department of Museums, Government of Tamil Nadu, Book 314

Source File: Department of Museums, Government of Tamil Nadu, Book 314

Source File: Department of Museums, Government of Tamil Nadu, Book 314

Source File: Department of Museums, Government of Tamil Nadu, Book 314

This article is from Cardiovascular Journal of Africa , volume 19 . Abstract Summary: The cardiovascular effects of mollic acid glucoside (MAG), a 1α-hydroxycycloartenoid saponin extractive from Combretum molle R Br ex G Don (Combretaceae) leaf, have been investigated in some experimental animal paradigms. The plant extract (MAG, 5–80 μg/ml) produced concentration-dependent, significant (p < 0.05–0.001) negative inotropic and negative chronotropic effects on guinea pig isolated electrically driven left, and spontaneously beating right atrial muscle preparations, respectively. MAG also significantly reduced (p < 0.05–0.001) or abolished, in a concentration-dependent manner, the rhythmic, spontaneous contractions of portal veins isolated from healthy, normal Wistar rats.Like acetylcholine (ACh, 10-8–10-5 M), the plant extract (5–80 μg/ml) produced concentration-related relaxations of rat isolated endothelium-containing thoracic aortic rings pre-contracted with noradrenaline (NA, 10-10–10-5 M). The vasorelaxant effects of MAG in the aortic rings were markedly inhibited or annulled by NG-nitro-L-arginine methyl ester (L-NAME, 10-5 M), a nitric oxide synthase inhibitor. Furthermore, MAG (2.5–40 mg/kg iv) caused dose-related, transient but significant reductions (p < 0.05–0.001) in the systemic arterial blood pressures and heart rates of anaesthetised normotensive and hypertensive rats.The results of this laboratory animal study indicate that MAG caused bradycardia, vasorelaxation and hypotension in the mammalian experimental models used. The vasorelaxant action of MAG was endothelium dependent, and was therefore possibly dependent on the synthesis and release of nitric oxide (NO). The findings of this study suggest that Combretum molle leaf may be used as a natural supplementary remedy in essential hypertension and in certain cases of cardiac dysfunctions in rural African communities.

This article is from Cardiovascular Journal of Africa , volume 19 . Abstract Summary: The cardiovascular effects of mollic acid glucoside (MAG), a 1α-hydroxycycloartenoid saponin extractive from Combretum molle R Br ex G Don (Combretaceae) leaf, have been investigated in some experimental animal paradigms. The plant extract (MAG, 5–80 μg/ml) produced concentration-dependent, significant (p < 0.05–0.001) negative inotropic and negative chronotropic effects on guinea pig isolated electrically driven left, and spontaneously beating right atrial muscle preparations, respectively. MAG also significantly reduced (p < 0.05–0.001) or abolished, in a concentration-dependent manner, the rhythmic, spontaneous contractions of portal veins isolated from healthy, normal Wistar rats.Like acetylcholine (ACh, 10-8–10-5 M), the plant extract (5–80 μg/ml) produced concentration-related relaxations of rat isolated endothelium-containing thoracic aortic rings pre-contracted with noradrenaline (NA, 10-10–10-5 M). The vasorelaxant effects of MAG in the aortic rings were markedly inhibited or annulled by NG-nitro-L-arginine methyl ester (L-NAME, 10-5 M), a nitric oxide synthase inhibitor. Furthermore, MAG (2.5–40 mg/kg iv) caused dose-related, transient but significant reductions (p < 0.05–0.001) in the systemic arterial blood pressures and heart rates of anaesthetised normotensive and hypertensive rats.The results of this laboratory animal study indicate that MAG caused bradycardia, vasorelaxation and hypotension in the mammalian experimental models used. The vasorelaxant action of MAG was endothelium dependent, and was therefore possibly dependent on the synthesis and release of nitric oxide (NO). The findings of this study suggest that Combretum molle leaf may be used as a natural supplementary remedy in essential hypertension and in certain cases of cardiac dysfunctions in rural African communities.

This article is from Cardiovascular Journal of Africa , volume 19 . Abstract Summary: The cardiovascular effects of mollic acid glucoside (MAG), a 1α-hydroxycycloartenoid saponin extractive from Combretum molle R Br ex G Don (Combretaceae) leaf, have been investigated in some experimental animal paradigms. The plant extract (MAG, 5–80 μg/ml) produced concentration-dependent, significant (p < 0.05–0.001) negative inotropic and negative chronotropic effects on guinea pig isolated electrically driven left, and spontaneously beating right atrial muscle preparations, respectively. MAG also significantly reduced (p < 0.05–0.001) or abolished, in a concentration-dependent manner, the rhythmic, spontaneous contractions of portal veins isolated from healthy, normal Wistar rats.Like acetylcholine (ACh, 10-8–10-5 M), the plant extract (5–80 μg/ml) produced concentration-related relaxations of rat isolated endothelium-containing thoracic aortic rings pre-contracted with noradrenaline (NA, 10-10–10-5 M). The vasorelaxant effects of MAG in the aortic rings were markedly inhibited or annulled by NG-nitro-L-arginine methyl ester (L-NAME, 10-5 M), a nitric oxide synthase inhibitor. Furthermore, MAG (2.5–40 mg/kg iv) caused dose-related, transient but significant reductions (p < 0.05–0.001) in the systemic arterial blood pressures and heart rates of anaesthetised normotensive and hypertensive rats.The results of this laboratory animal study indicate that MAG caused bradycardia, vasorelaxation and hypotension in the mammalian experimental models used. The vasorelaxant action of MAG was endothelium dependent, and was therefore possibly dependent on the synthesis and release of nitric oxide (NO). The findings of this study suggest that Combretum molle leaf may be used as a natural supplementary remedy in essential hypertension and in certain cases of cardiac dysfunctions in rural African communities.

This article is from Cardiovascular Journal of Africa , volume 19 . Abstract Summary: The cardiovascular effects of mollic acid glucoside (MAG), a 1α-hydroxycycloartenoid saponin extractive from Combretum molle R Br ex G Don (Combretaceae) leaf, have been investigated in some experimental animal paradigms. The plant extract (MAG, 5–80 μg/ml) produced concentration-dependent, significant (p < 0.05–0.001) negative inotropic and negative chronotropic effects on guinea pig isolated electrically driven left, and spontaneously beating right atrial muscle preparations, respectively. MAG also significantly reduced (p < 0.05–0.001) or abolished, in a concentration-dependent manner, the rhythmic, spontaneous contractions of portal veins isolated from healthy, normal Wistar rats.Like acetylcholine (ACh, 10-8–10-5 M), the plant extract (5–80 μg/ml) produced concentration-related relaxations of rat isolated endothelium-containing thoracic aortic rings pre-contracted with noradrenaline (NA, 10-10–10-5 M). The vasorelaxant effects of MAG in the aortic rings were markedly inhibited or annulled by NG-nitro-L-arginine methyl ester (L-NAME, 10-5 M), a nitric oxide synthase inhibitor. Furthermore, MAG (2.5–40 mg/kg iv) caused dose-related, transient but significant reductions (p < 0.05–0.001) in the systemic arterial blood pressures and heart rates of anaesthetised normotensive and hypertensive rats.The results of this laboratory animal study indicate that MAG caused bradycardia, vasorelaxation and hypotension in the mammalian experimental models used. The vasorelaxant action of MAG was endothelium dependent, and was therefore possibly dependent on the synthesis and release of nitric oxide (NO). The findings of this study suggest that Combretum molle leaf may be used as a natural supplementary remedy in essential hypertension and in certain cases of cardiac dysfunctions in rural African communities.

This article is from Cardiovascular Journal of Africa , volume 19 . Abstract Summary: The cardiovascular effects of mollic acid glucoside (MAG), a 1α-hydroxycycloartenoid saponin extractive from Combretum molle R Br ex G Don (Combretaceae) leaf, have been investigated in some experimental animal paradigms. The plant extract (MAG, 5–80 μg/ml) produced concentration-dependent, significant (p < 0.05–0.001) negative inotropic and negative chronotropic effects on guinea pig isolated electrically driven left, and spontaneously beating right atrial muscle preparations, respectively. MAG also significantly reduced (p < 0.05–0.001) or abolished, in a concentration-dependent manner, the rhythmic, spontaneous contractions of portal veins isolated from healthy, normal Wistar rats.Like acetylcholine (ACh, 10-8–10-5 M), the plant extract (5–80 μg/ml) produced concentration-related relaxations of rat isolated endothelium-containing thoracic aortic rings pre-contracted with noradrenaline (NA, 10-10–10-5 M). The vasorelaxant effects of MAG in the aortic rings were markedly inhibited or annulled by NG-nitro-L-arginine methyl ester (L-NAME, 10-5 M), a nitric oxide synthase inhibitor. Furthermore, MAG (2.5–40 mg/kg iv) caused dose-related, transient but significant reductions (p < 0.05–0.001) in the systemic arterial blood pressures and heart rates of anaesthetised normotensive and hypertensive rats.The results of this laboratory animal study indicate that MAG caused bradycardia, vasorelaxation and hypotension in the mammalian experimental models used. The vasorelaxant action of MAG was endothelium dependent, and was therefore possibly dependent on the synthesis and release of nitric oxide (NO). The findings of this study suggest that Combretum molle leaf may be used as a natural supplementary remedy in essential hypertension and in certain cases of cardiac dysfunctions in rural African communities.

This article is from Cardiovascular Journal of Africa , volume 19 . Abstract Summary: The cardiovascular effects of mollic acid glucoside (MAG), a 1α-hydroxycycloartenoid saponin extractive from Combretum molle R Br ex G Don (Combretaceae) leaf, have been investigated in some experimental animal paradigms. The plant extract (MAG, 5–80 μg/ml) produced concentration-dependent, significant (p < 0.05–0.001) negative inotropic and negative chronotropic effects on guinea pig isolated electrically driven left, and spontaneously beating right atrial muscle preparations, respectively. MAG also significantly reduced (p < 0.05–0.001) or abolished, in a concentration-dependent manner, the rhythmic, spontaneous contractions of portal veins isolated from healthy, normal Wistar rats.Like acetylcholine (ACh, 10-8–10-5 M), the plant extract (5–80 μg/ml) produced concentration-related relaxations of rat isolated endothelium-containing thoracic aortic rings pre-contracted with noradrenaline (NA, 10-10–10-5 M). The vasorelaxant effects of MAG in the aortic rings were markedly inhibited or annulled by NG-nitro-L-arginine methyl ester (L-NAME, 10-5 M), a nitric oxide synthase inhibitor. Furthermore, MAG (2.5–40 mg/kg iv) caused dose-related, transient but significant reductions (p < 0.05–0.001) in the systemic arterial blood pressures and heart rates of anaesthetised normotensive and hypertensive rats.The results of this laboratory animal study indicate that MAG caused bradycardia, vasorelaxation and hypotension in the mammalian experimental models used. The vasorelaxant action of MAG was endothelium dependent, and was therefore possibly dependent on the synthesis and release of nitric oxide (NO). The findings of this study suggest that Combretum molle leaf may be used as a natural supplementary remedy in essential hypertension and in certain cases of cardiac dysfunctions in rural African communities.

This article is from Cardiovascular Journal of Africa , volume 19 . Abstract Summary: The cardiovascular effects of mollic acid glucoside (MAG), a 1α-hydroxycycloartenoid saponin extractive from Combretum molle R Br ex G Don (Combretaceae) leaf, have been investigated in some experimental animal paradigms. The plant extract (MAG, 5–80 μg/ml) produced concentration-dependent, significant (p < 0.05–0.001) negative inotropic and negative chronotropic effects on guinea pig isolated electrically driven left, and spontaneously beating right atrial muscle preparations, respectively. MAG also significantly reduced (p < 0.05–0.001) or abolished, in a concentration-dependent manner, the rhythmic, spontaneous contractions of portal veins isolated from healthy, normal Wistar rats.Like acetylcholine (ACh, 10-8–10-5 M), the plant extract (5–80 μg/ml) produced concentration-related relaxations of rat isolated endothelium-containing thoracic aortic rings pre-contracted with noradrenaline (NA, 10-10–10-5 M). The vasorelaxant effects of MAG in the aortic rings were markedly inhibited or annulled by NG-nitro-L-arginine methyl ester (L-NAME, 10-5 M), a nitric oxide synthase inhibitor. Furthermore, MAG (2.5–40 mg/kg iv) caused dose-related, transient but significant reductions (p < 0.05–0.001) in the systemic arterial blood pressures and heart rates of anaesthetised normotensive and hypertensive rats.The results of this laboratory animal study indicate that MAG caused bradycardia, vasorelaxation and hypotension in the mammalian experimental models used. The vasorelaxant action of MAG was endothelium dependent, and was therefore possibly dependent on the synthesis and release of nitric oxide (NO). The findings of this study suggest that Combretum molle leaf may be used as a natural supplementary remedy in essential hypertension and in certain cases of cardiac dysfunctions in rural African communities.

This article is from Cardiovascular Journal of Africa , volume 19 . Abstract Summary: The cardiovascular effects of mollic acid glucoside (MAG), a 1α-hydroxycycloartenoid saponin extractive from Combretum molle R Br ex G Don (Combretaceae) leaf, have been investigated in some experimental animal paradigms. The plant extract (MAG, 5–80 μg/ml) produced concentration-dependent, significant (p < 0.05–0.001) negative inotropic and negative chronotropic effects on guinea pig isolated electrically driven left, and spontaneously beating right atrial muscle preparations, respectively. MAG also significantly reduced (p < 0.05–0.001) or abolished, in a concentration-dependent manner, the rhythmic, spontaneous contractions of portal veins isolated from healthy, normal Wistar rats.Like acetylcholine (ACh, 10-8–10-5 M), the plant extract (5–80 μg/ml) produced concentration-related relaxations of rat isolated endothelium-containing thoracic aortic rings pre-contracted with noradrenaline (NA, 10-10–10-5 M). The vasorelaxant effects of MAG in the aortic rings were markedly inhibited or annulled by NG-nitro-L-arginine methyl ester (L-NAME, 10-5 M), a nitric oxide synthase inhibitor. Furthermore, MAG (2.5–40 mg/kg iv) caused dose-related, transient but significant reductions (p < 0.05–0.001) in the systemic arterial blood pressures and heart rates of anaesthetised normotensive and hypertensive rats.The results of this laboratory animal study indicate that MAG caused bradycardia, vasorelaxation and hypotension in the mammalian experimental models used. The vasorelaxant action of MAG was endothelium dependent, and was therefore possibly dependent on the synthesis and release of nitric oxide (NO). The findings of this study suggest that Combretum molle leaf may be used as a natural supplementary remedy in essential hypertension and in certain cases of cardiac dysfunctions in rural African communities.

This article is from Cardiovascular Journal of Africa , volume 19 . Abstract Summary: The cardiovascular effects of mollic acid glucoside (MAG), a 1α-hydroxycycloartenoid saponin extractive from Combretum molle R Br ex G Don (Combretaceae) leaf, have been investigated in some experimental animal paradigms. The plant extract (MAG, 5–80 μg/ml) produced concentration-dependent, significant (p < 0.05–0.001) negative inotropic and negative chronotropic effects on guinea pig isolated electrically driven left, and spontaneously beating right atrial muscle preparations, respectively. MAG also significantly reduced (p < 0.05–0.001) or abolished, in a concentration-dependent manner, the rhythmic, spontaneous contractions of portal veins isolated from healthy, normal Wistar rats.Like acetylcholine (ACh, 10-8–10-5 M), the plant extract (5–80 μg/ml) produced concentration-related relaxations of rat isolated endothelium-containing thoracic aortic rings pre-contracted with noradrenaline (NA, 10-10–10-5 M). The vasorelaxant effects of MAG in the aortic rings were markedly inhibited or annulled by NG-nitro-L-arginine methyl ester (L-NAME, 10-5 M), a nitric oxide synthase inhibitor. Furthermore, MAG (2.5–40 mg/kg iv) caused dose-related, transient but significant reductions (p < 0.05–0.001) in the systemic arterial blood pressures and heart rates of anaesthetised normotensive and hypertensive rats.The results of this laboratory animal study indicate that MAG caused bradycardia, vasorelaxation and hypotension in the mammalian experimental models used. The vasorelaxant action of MAG was endothelium dependent, and was therefore possibly dependent on the synthesis and release of nitric oxide (NO). The findings of this study suggest that Combretum molle leaf may be used as a natural supplementary remedy in essential hypertension and in certain cases of cardiac dysfunctions in rural African communities.

http://uf.catalog.fcla.edu/uf.jsp?st=UF005461644&ix=pm&I=0&V=D&pm=1

http://uf.catalog.fcla.edu/uf.jsp?st=UF005461644&ix=pm&I=0&V=D&pm=1

http://uf.catalog.fcla.edu/uf.jsp?st=UF005461644&ix=pm&I=0&V=D&pm=1

Phytoconstituents present in the ethanolic extract of Combretum hispidum leaves were explored by Gas Chromatography Mass Spectrometry analysis. The compounds were identified by the gas chromatography coupled with the mass spectrometry. The molecular weight and structure of the compounds of Combretum hispidum leaves were ascertained by interpretation of the spectrum of GC MS using the database of National Institute of Standard and Technology NIST . GC MS analysis of Combretum hispidum leaves revealed the presence of nineteen biological active compounds. The compounds are N Tosyl dl 3,4 dehydroprolylglycine, ethyl ester, 1 n Butoxy 2,2,3,3 tetramethylaziridine, 2 Butenoic acid, 3 methyl 4 tetrahydro 3,4 dihydroxy 5 3 2 hydroxy 1 methylpropyl oxiranyl methyl 2H pyran , Cobalt, octacarbonyl zinc di , 2Co Zn , 6 Dehydroxy 2,3,3,4,4,5,7 hepta O methylisoorientin, 2 naphthalenol, 3 5 3 nitrophenyl 1,3,4 oxadiazol 2 yl , L Proline, N 1 naphthoyl , dodecyl ester, 3,6 Dispirocyclohexyl 1,2,3,4,5,6,7,8 octahydro 1,8 acridinedione, Sarcosine, N 2 chloroethoxycarbonyl , heptadecyl ester, Cycloocta 1,2 b 4,3 b 5,6 b 8,7 b tetrakis 1 benzothiophene, Butanoic acid, 2 chloro 3 methyl , 4 5 heptyl 2 pyrimidinyl phenyl ester, Friedooleanan 1 one, 3,24 dihydroxy , 9 O Methyl 4,5 deoxymaytansino, Ditelluride, di 1 naphthalenyl, tert Butylstibinous acid thioanhydride, l Leucine, N methyl n pentadecafluorocarbonyl , octadecyl ester, 2,5 Dichloro N ethyl N phenyl benzamide, 2 Thiophenylacetic acid, 2,2,2 trifluoroethyl ester, Methyl 8 5 methoxycarbonyl methyl 2 furyl octanoate. It was concluded that the bioactive compounds support the use of C. hispidum leaves in the treatment of diseases like cancer, anaphylactic shock, renal failure, diabetes and hypertension. O. V. Ikpeazu | I. E. Otuokere | K. K. Igwe "GC–MS Analysis of Bioactive Compounds Present in Ethanol Extract of Combretum Hispidum (Laws) (Combretaceae) Leaves" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-4 | Issue-5 , August 2020, URL: https://www.ijtsrd.com/papers/ijtsrd31868.pdf Paper Url :https://www.ijtsrd.com/chemistry/biochemistry/31868/gc–ms-analysis-of-bioactive-compounds-present-in-ethanol-extract-of-combretum-hispidum-laws-combretaceae-leaves/o-v-ikpeazu

This article is from ZooKeys . Abstract AbstractRecent studies indicate that the discriminatory power of the core DNA barcodes (rbcLa + matK) for land plants may have been overestimated since their performance have been tested only on few closely related species. In this study we focused mainly on how the addition of complementary barcodes (nrITS and trnH-psbA) to the core barcodes will affect the performance of the core barcodes in discriminating closely related species from family to section levels. In general, we found that the core barcodes performed poorly compared to the various combinations tested. Using multiple criteria, we finally advocated for the use of the core + trnH-psbA as potential DNA barcode for the family Combretaceae at least in southern Africa. Our results also indicate that the success of DNA barcoding in discriminating closely related species may be related to evolutionary and possibly the biogeographic histories of the taxonomic group tested.

This article is from ZooKeys . Abstract AbstractRecent studies indicate that the discriminatory power of the core DNA barcodes (rbcLa + matK) for land plants may have been overestimated since their performance have been tested only on few closely related species. In this study we focused mainly on how the addition of complementary barcodes (nrITS and trnH-psbA) to the core barcodes will affect the performance of the core barcodes in discriminating closely related species from family to section levels. In general, we found that the core barcodes performed poorly compared to the various combinations tested. Using multiple criteria, we finally advocated for the use of the core + trnH-psbA as potential DNA barcode for the family Combretaceae at least in southern Africa. Our results also indicate that the success of DNA barcoding in discriminating closely related species may be related to evolutionary and possibly the biogeographic histories of the taxonomic group tested.

This article is from ZooKeys . Abstract AbstractRecent studies indicate that the discriminatory power of the core DNA barcodes (rbcLa + matK) for land plants may have been overestimated since their performance have been tested only on few closely related species. In this study we focused mainly on how the addition of complementary barcodes (nrITS and trnH-psbA) to the core barcodes will affect the performance of the core barcodes in discriminating closely related species from family to section levels. In general, we found that the core barcodes performed poorly compared to the various combinations tested. Using multiple criteria, we finally advocated for the use of the core + trnH-psbA as potential DNA barcode for the family Combretaceae at least in southern Africa. Our results also indicate that the success of DNA barcoding in discriminating closely related species may be related to evolutionary and possibly the biogeographic histories of the taxonomic group tested.

This article is from ZooKeys . Abstract AbstractRecent studies indicate that the discriminatory power of the core DNA barcodes (rbcLa + matK) for land plants may have been overestimated since their performance have been tested only on few closely related species. In this study we focused mainly on how the addition of complementary barcodes (nrITS and trnH-psbA) to the core barcodes will affect the performance of the core barcodes in discriminating closely related species from family to section levels. In general, we found that the core barcodes performed poorly compared to the various combinations tested. Using multiple criteria, we finally advocated for the use of the core + trnH-psbA as potential DNA barcode for the family Combretaceae at least in southern Africa. Our results also indicate that the success of DNA barcoding in discriminating closely related species may be related to evolutionary and possibly the biogeographic histories of the taxonomic group tested.