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This article is from BMJ Open , volume 4 . Abstract Introduction: Suicide is an important public health problem and one of the most common causes of death throughout the world. Suicidal behaviour is complex, and its causes are multifactorial. Case–control studies have reported an association between an alteration of the serotonin system and suicidal behaviour. Recently, it has been suggested that the 5-HTRC2 serotonin receptor gene is involved in the pathogenesis of suicidal behaviour. Methods and analysis: To evaluate the role of the 5-HTR2C gene in suicidal behaviour, we will perform a systematic review and a meta-analysis of worldwide reports that have investigated the association between the serotonin system and suicidal behaviour. This analysis will be reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. Studies deemed fit for inclusion in the systematic review will be scored for methodological quality using the Newcastle-Ottawa Assessment Scale (NOS). The inclusion criteria will be to present independent data, to be case–control studies and to be published in journal peer reviews. To generate more accurate analyses, we will grade the reports using the GRADES scale procedures. Ethics and dissemination: This study will describe the association between the HTR2C gene and suicidal behaviour. The results will be reported in a peer-reviewed publication and in scientific presentations in Mexico and throughout the world. Trial registration number: PROSPERO CRD42014009213.

1Monk and the Hangman's Daughter

By Ambrose Bierce and Adolphe Danziger de Castro

A tragic but very captivating tale of a monk in the 17th century.

Esta novela de Rosalía de Castro, es considerada por la crítica como la más interesante de la autora. Calificada por ella como "cuento extraño". Compuesta por veinticuatro capítulos a modo dramático, entre un hombre y una musa: "Ya que has acudido a mi llamamiento, ¡oh musa!, escúchame atenta y propicia, y haz que se cumpla mi más ferviente deseo" La obra es una "sátira fantástica" a la hipocresía de la sociedad madrileña. - Summary by Montse González.

3Last Test

By Adolphe Danziger de Castro

This is a supernatural tale about Dr. Alfred Clarendon’s quest to find a cure for the host illnesses that plague mankind. He performs risky experiments using specimens and samples he gathered world wide, which go out of control. Is there anyone who can untangle this mystery? (Summary by kirk202)

"A mi madre", es uno de los primeros poemarios escritos por la autora gallega y editado por D. Juan Compañel en 1863. Como en muchas de sus obras, aquí Rosalía refleja una idea romántica, ofrece una estética sin grandilocuencias, muestra sensibilidad, la expresión interior suprema, la subjetividad del "yo poeta". No obstante, estos versos conforman una elegía, una oda a su madre fallecida. (Introducción por Lu)