Differences In Resting-state Functional Connectivity Of Temperament-based Profiles Among Youth With ADHD In The ABCD Study - Info and Reading Options
By Jaden Sangoi
“Differences In Resting-state Functional Connectivity Of Temperament-based Profiles Among Youth With ADHD In The ABCD Study” Metadata:
- Title: ➤ Differences In Resting-state Functional Connectivity Of Temperament-based Profiles Among Youth With ADHD In The ABCD Study
- Author: Jaden Sangoi
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- Internet Archive ID: osf-registrations-gcdsx-v1
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DSM-5-TR diagnostic criteria does not fully address behavioral and clinical heterogeneity inherent to ADHD; however, temperament-based profiles may help explain biological heterogeneity within the disorder. Temperament profiles have been defined and replicated among youth with ADHD and have demonstrated unique patterns of resting-state functional connectivity within a small sample. Two temperament profiles have been identified by Kozlowski et al. (this special issue) in the ABCD Study, and the present study sought to replicate and validate documented resting-state patterns. Functional connectivity between bilateral amygdalae and 12 Gordon networks was compared between profiles and typically developing (TD) youth. Surgent youth demonstrated stronger right amygdala-dorsal attention network connectivity (ß=.0434) and right amygdala-retrosplenial temporal network connectivity (ß=.0442) compared to TD youth. Irritable youth demonstrated unique connectivity patterns compared to TD and surgent youth; however, effects did not survive correction for multiple comparisons. Findings provide support for future research examining temperament profiles among ADHD youth.
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- Added Date: 2025-08-04 19:05:20
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