Current Concepts in Movement Disorder Management - Info and Reading Options

Harvard Library:

This book summarizes the current state of movement disorder management and the role of surgical therapies as an alternative to medication. Following a chapter on the history of movement disorder surgery, leaders in their fields describe the pathophysiology, functional neuroanatomy, clinical presentation, and medical management of Parkinson’s disease, dystonia, and essential tremor. This is followed by chapters on the spectrum of movement disorder surgery itself, from the lesioning procedures of radiofrequency ablation, stereotactic radiosurgery, and high-frequency ultrasound to the modulatory procedures of “asleep”, image-guided deep brain stimulation (DBS) and “awake”, microelectrode-guided DBS. The final chapters focus on closed-loop DBS, drug-delivery, gene therapy, and other emerging neurosurgical therapies, highlighting long-standing experimental strategies that are reaching exciting phases of clinical translation. This volume is a valuable tool for accessing the wide spectrum of concepts that currently define this dynamic field.

Open Data:

Cover -- Front Matter -- Contents -- VIISeries Editor's Note -- Preface -- The History of Movement Disorder Brain Surgery -- Abstract -- The Pre Stereotactic Era -- The Early Era of Stereotactic Brain Surgery -- The Era of Spreading Stereotactic Techniques -- The Era of Decline of Stereotactic Surgery -- The Early Transplant Era -- The Era of Advanced Stereotactic Imaging and Mapping -- The Deep Brain Stimulation Era -- The Era of Radiosurgery -- The Evolution of Frameless Technologies and Intraoperative MRI -- Conclusions -- References -- Pathophysiologic Basis of Movement Disorders -- Abstract -- Introduction -- Relevant Brain Circuit Anatomy -- Parkinson's Disease -- Dystonia -- Essential Tremor -- Conclusions -- References -- Clinical Presentation and Prognosis of Common Movement Disorders -- Abstract -- Introduction -- Parkinsonian Syndromes -- Tremor -- Dystonia -- Tics and Tourette Syndrome -- Conclusion -- References -- Medical Management of Movement Disorders -- Abstract -- Parkinson's Disease -- Early Stage -- Advanced Stage -- Essential Tremor -- Dystonia -- Chorea -- References -- Functional Anatomy of Basal Ganglia Circuits with the Cerebral Cortex and the Cerebellum -- Abstract -- Cortico-Basal Ganglia-Thalamo-Cortical Circuits -- Macro-Architecture of Cortico-Basal Ganglia-Thalamo-Cortical Loops -- The Basal Ganglia are Interconnected with the Cerebellum -- References -- Diffusion Tensor Imaging of the Basal Ganglia for Functional Neurosurgery Applications -- Abstract -- Introduction -- DTI Imaging: Atlas versus Patient-Based Targeting -- Diffusion Tensor Model: Brief Principles of Diffusion Imaging and Tractography Algorithms Available -- DTI of the Basal Ganglia -- Subthalamic Nucleus -- Globus Pallidus -- Thalamus -- Use of DTI in Movement Disorder Surgery: Implications for Non-Invasive Surgical Methods -- Conclusions

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