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  • Title: ➤  Assessing The Role Of Vascular Risk Factors In Dementia: Mendelian Randomization Meta-analysis And Comparison With Observational Estimates
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In this paper, we report the causative role of modifiable vascular risk factors in dementia through meta-analysis of Mendelian Randomization studies. Our results show that apart from genetically predicted higher body mass index, no evidence was found to support an association between dementia and other genetically predicted vascular risk factors. This is significant because many modifiable risk factors associated with dementia in observational studies may not play a causative role. This should be of particular interest to readers in neurology and public health. This article has been published as a pre-print on medRxiv. There are no conflicts of interest. All authors are agreeing to the submission of this article.

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  • Added Date: 2022-05-18 10:58:41
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