Explore: Endochondral Ossification

Endochondral ossification is one of the two essential pathways by which bone tissue is produced during fetal development and bone repair of the mammalian

Intramembranous ossification is the direct laying down of bone into the primitive connective tissue (mesenchyme), while endochondral ossification involves cartilage

fractures and the rudimentary formation of bones of the head. Unlike endochondral ossification, which is the other process by which bone tissue is created during

called ossification. During the fetal stage of development this occurs by two processes: intramembranous ossification and endochondral ossification. Intramembranous

month. Ossification starts as membranous ossification before birth. After birth, the cartilaginous components would undergo endochondral ossification. The

emerging role of chondrocyte-to-osteoblast transdifferentiation in endochondral ossification". Bone Research. 6: 19. doi:10.1038/s41413-018-0021-z. ISSN 2095-4700

dermal bones formed by intramembranous ossification, though the temporal bones are formed by endochondral ossification. The endocranium, the bones supporting

the bone. This disorder is defined as a focal disturbance of endochondral ossification and is regarded as having a multifactorial cause, so no one thing

differentiation when they become hypertrophic, which happens during endochondral ossification. This last stage is characterized by major phenotypic changes

flat bone that lies in the middle front part of the rib cage. It is endochondral in origin. It probably first evolved in early tetrapods as an extension